J Retin.  2023 May;8(1):58-61. 10.21561/jor.2023.8.1.58.

Relapse of Ocular Lymphoma following Primary Testicular Diffuse Large B-cell Lymphoma

Affiliations
  • 1Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Abstract

Purpose
To describe the first case of ocular relapse of primary testicular B-cell lymphoma in a South Korean male.
Case summary
A 60-year-old man with a history of left testicular diffuse large B-cell lymphoma diagnosed four years prior to this presentation complained of decreased vision in his right eye for the past two months despite treatment for uveitis. He had a history of brain relapse of diffuse large B-cell lymphoma two years prior and had been in secondary complete remission for two years. Ophthalmologic examination revealed uveitis with a pseudohypopyon and a mass-like lesion on the iris. Incisional biopsy of the iris mass revealed diffuse large B-cell lymphoma. A systemic work up showed no evidence of lymphoma relapse elsewhere, and additional systemic chemotherapy was planned.
Conclusions
This case is the first report of ocular involvement of testicular diffuse large B-cell lymphoma in South Korea. Clinicians should be aware of ocular relapse in patients with a history of testicular lymphoma who complain of eye symptoms.

Keyword

Diffuse large B-cell lymphoma; Intraocular lymphoma; Lymphoma; Non-Hodgkin
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