Korean J Dermatol.  2007 Feb;45(2):188-193.

Primary Cutaneous T-cell/histiocyte-rich B-cell Lymphoma

  • 1Department of Dermatology, College of Medicine, Cheju National University, Jeju, Korea. rulid@cheju.ac.kr


T-cell/histiocyte-rich B-cell lymphoma is a recently-described morphologic variant of diffuse large B-cell lymphoma which can be confused with nodular lymphocyte-predominant Hodgkin's lymphoma and reactive lymphadenopathies. T-cell/histiocyte-rich B-cell lymphoma is characterized by a few large, atypical B-lymphoid cells set in a background containing numerous reactive small T-cells and non-epithelioid histiocytes. This lymphoma follows a natural history similar to those of traditional diffuse large B-cell lymphoma. Although rare, the primary cutaneous form appears to have a better prognosis than its nodal counterpart. We report on a case of a 52-year-old woman with primary cutaneous T-cell/ histiocyte-rich B-cell lymphoma. To our knowledge, this is the first case of T-cell/histiocyte-rich B-cell lymphoma, with or without skin involvement, reported in the Korean literature.


T-cell/histiocyte-rich B-cell lymphoma
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