Imaging Sci Dent.  2022 Dec;52(4):435-440. 10.5624/isd.20220143.

Mucormycosis-related osteomyelitis of the maxilla in a post-COVID-19 patient

Affiliations
  • 1Department of Oral and Maxillofacial Radiology, School of Dentistry, Seoul National University, Korea
  • 2Department of Oral Medicine, University of Dental Medicine, Mandalay, Myanmar
  • 3Department of Oral and Maxillofacial Radiology, Seoul National University Dental Hospital, Seoul, Korea

Abstract

Mucormycosis is a rare, invasive fungal infection that progresses aggressively and requires prompt surgery and appropriate treatment. The number of cases of mucormycosis in coronavirus disease 2019 (COVID-19) patients has recently increased, and patients with uncontrolled diabetes mellitus are particularly at an elevated risk of infection. This report presents a case of mucormycosis-related osteomyelitis of the maxilla in a 37-year-old man with diabetes mellitus. The patient complained of severe and persistent pain in the right maxilla, accompanied by increased tooth mobility and headache. On contrast-enhanced computed tomographic images, gas-forming osteomyelitis of the right maxilla was observed. Destruction of the maxilla and palatine bone then proceeded aggressively. Sequestrectomy was performed on the right maxilla, and the histopathological diagnosis was mucormycosis. Further investigation after the first operation revealed the patient's history of COVID-19 infection.

Keyword

Mucormycosis; Maxilla; Osteomyelitis; Diabetes Mellitus; COVID-19
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