Tissue Eng Regen Med.  2022 Oct;19(5):927-960. 10.1007/s13770-022-00459-z.

An Insight of Nanomaterials in Tissue Engineering from Fabrication to Applications

Affiliations
  • 1Department of Biochemistry, University of Delhi, Delhi, India
  • 2Department of Chemistry, Kirori Mal College, University of Delhi, Delhi, India
  • 3Department of Chemistry, University of Delhi, Delhi, India
  • 4Department of Chemistry, Sri Venkateswara College, University of Delhi, Delhi, India
  • 5Department of Chemistry, Acharya Narendra Dev College, University of Delhi, Delhi, India
  • 6Department of Chemistry, SRM Institute of Science and Technology, Delhi NCR Campus, Ghaziabad, Uttar Pradesh, India
  • 7Department of Chemistry, Atma Ram Sanatan Dharma College, University of Delhi, Delhi, India
  • 8Special Centre for Nano Science, Jawaharlal Nehru University, Delhi, India

Abstract

Tissue engineering is a research domain that deals with the growth of various kinds of tissues with the help of synthetic composites. With the culmination of nanotechnology and bioengineering, tissue engineering has emerged as an exciting domain. Recent literature describes its various applications in biomedical and biological sciences, such as facilitating the growth of tissue and organs, gene delivery, biosensor-based detection, etc. It deals with the development of biomimetics to repair, restore, maintain and amplify or strengthen several biological functions at the level of tissue and organs. Herein, the synthesis of nanocomposites based on polymers, along with their classification as conductive hydrogels and bioscaffolds, is comprehensively discussed. Furthermore, their implementation in numerous tissue engineering and regenerative medicine applications is also described. The limitations of tissue engineering are also discussed here. The present review highlights and summarizes the latest progress in the tissue engineering domain directed at functionalized nanomaterials.

Keyword

Tissue engineering; Nanomaterials; Nanotechnology; Regenerative medicine; Biomimetics; Conductive hydrogels; Polymers; Scaffolds
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