Korean J Dermatol.  2006 Apr;44(4):508-511.

A Case of Verruciform Xanthoma Presenting as Leukoplakia on the Lower Lip

  • 1Department of Dermatology, College of Medicine, Gyeongsang National University, Jinju, Korea.
  • 2Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea. deroh@nongae.gsnu.ac.kr


Leukoplakia is a fixed, predominantly white-lesion of the mucosa. It is most often seen on the oral and anogenital mucosa. Leukoplakia should be biopsied to determine the true histopathologic diagnosis. Verruciform xanthoma is composed of asymptomatic, usually solitary, flat plaques or warty lesions. They may vary in color from gray to pink or yellow. Its pathogenesis is still unknown and usual site is the oral cavity. Histopathologically, it is characterized by verrucous epidermal hyperplasia with aggregates of foam cells in the dermal papillae. A review of literature indicated that verruciform xanthoma presenting as a whitish plaque on the lower lip was very rare. We describe a 70-year-old woman with verruciform xanthoma who presented with a whitish plaque on her lower lip.


Leukoplakia; Lower lip; Verruciform xanthoma
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