Clin Endosc.  2022 Mar;55(2):313-314. 10.5946/ce.2022.039.

A Rare Cause of Subepithelial Tumor in the Gastric Fundus

Affiliations
  • 1Department of Internal Medicine, Pusan National University College of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
  • 2Department of Pathology, Pusan National University Hospital, Busan, Korea


Figure

  • Fig. 1. (A) Initial endoscopy reveals a small subepithelial tumor on the posterior wall of the gastric fundus. (B) On endoscopic ultrasonography, the tumor presents as a heterogeneously hypoechoic lesion in the submucosal layer, measuring 0.8 cm in diameter. (C) On follow-up endoscopy 2 years later, the tumor has increased in size although no erosion or ulceration is noted. (D) Traction-assisted endoscopic submucosal dissection is performed. (E) The tumor is removed completely. (F) The inner surface of the resected specimen.

  • Fig. 2. (A) Histopathological examination reveals spindle cell proliferation and infiltration of lymphocytes and plasma cells in the submucosal layer (hematoxylin & eosin stain, ×200). (B) The spindle cells are immunopositive for CD34, and immunonegative for c-kit, smooth muscle actin, and S-100 protein (CD34 stain, ×100).


Reference

1. Albuquerque A, Rios E, Carneiro F, Macedo G. Evaluation of clinico-pathological features and Helicobacter pylori infection in gastric inflammatory fibroid polyps. Virchows Arch. 2014; 465:643–647.
2. Kawai A, Matsumoto H, Haruma K, et al. Rare case of gastric inflammatory fibroid polyp located at the fornix of the stomach and mimicking gastric cancer: a case report. Surg Case Rep. 2020; 6:292.
3. Kim GH, Park DY. A rare cause of gastric subepithelial tumor. Clin Endosc. 2020; 53:377–378.
4. Mavrogenis G, Herin M, Natale MD, Hassaini H. Resection of a gastric fibroid inflammatory polyp by means of endoscopic submucosal dissection: how deep is deep enough? Ann Gastroenterol. 2016; 29:380.
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