Korean J Helicobacter Up Gastrointest Res.  2021 Jun;21(2):106-114. 10.7704/kjhugr.2021.0006.

Subepithelial Tumor-like Gastric Cancer

Affiliations
  • 1Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea

Abstract

Subepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is often covered with normal mucosa. The mechanisms of occurrence of SET-like GC include: 1) excessive infiltration of lymphocytes in the cancer, 2) intensive secretion of mucin by mucinous adenocarcinoma, 3) excessive fibrosis around the cancer, and 4) adenocarcinoma arising from heterotopic gastric glands in the submucosa. It is important to be aware of the endoscopic features of SET-like GC to differentiate it from other subepithelial tumors, to recognize the possibility of SET-like GC, and to make a diagnosis before treatment. In this review, we summarized the epidemiologic and clinicopathologic characteristics of SET-like GC.

Keyword

Gastric cancer; Mucinous adenocarcinoma; Subepithelial tumor
Full Text Links
  • KJHUGR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr