Int J Thyroidol.  2021 Nov;14(2):170-174. 10.11106/ijt.2021.14.2.170.

Persistent Hypokalemic Paralysis in a Patient with Graves’ Disease and Gitelman Syndrome

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Medicine, Wonkwang University School of Medicine, Iksan, Korea

Abstract

Thyrotoxic periodic paralysis (TPP) is a potentially life-threatening condition. Graves’ disease accounts for the majority of cases of TPP. However, another diagnosis should be considered when repeated hypokalemic paralysis occurs in patients that maintain a euthyroid status. In this study, we report a case of persistent hypokalemic paralysis in a patient with Graves’ disease and Gitelman syndrome and provide a brief review of Gitelman syndrome focused on challenges with diagnosis and management when it is accompanied by TPP.

Keyword

Hypokalemic periodic paralysis; Graves; disease; Gitelman syndrome
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