J Korean Child Neurol Soc.  2013 Jun;21(2):68-72.

A Case of Thyrotoxic Periodic Paralysis in 17-Year-Old Adolescent

Affiliations
  • 1Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. sunjun@jbnu.ac.kr

Abstract

Thyrotoxic periodic paralysis (TPP) is a rare disease of muscle paralysis associated with hypokalemia and thyrotoxicosis. Hypokalemic periodic paralysis can be caused by potassium channelopathy or thyroid dysfunction. Thyrotoxic hypokalemic periodic paralysis is far more common in Asian males aged between 20 to 40 years and rare in children and adolescents. Clinical symptoms with motor paralysis were recovered just after treatment of potassium, propranolol, and methimazole. However, thyroid function tests were not normalized until 3 month treatment of methimazole and propranolol. We report a 17-year-old patient diagnosed with Graves' disease with TPP. Thyroid function test should including in periodic paralysis patient's evaluation.

Keyword

Thyrotoxic periodic paralysis; Hyperthyroidism; Graves disease; Adolescent

MeSH Terms

Adolescent
Aged
Asian Continental Ancestry Group
Channelopathies
Child
Graves Disease
Humans
Hyperthyroidism
Hypokalemia
Hypokalemic Periodic Paralysis
Male
Methimazole
Muscles
Paralysis
Potassium
Propranolol
Rare Diseases
Thyroid Function Tests
Thyroid Gland
Thyrotoxicosis
Methimazole
Potassium
Propranolol
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