Allergy Asthma Respir Dis.  2021 Oct;9(4):203-207. 10.4168/aard.2021.9.4.203.

Main epidemiological characteristics and natural history of pediatric allergic rhinitis

  • 1Department of Pediatrics, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Korea
  • 2Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
  • 3Department of Pediatrics, Asthma and Allergy Center, Inje University Sanggye Paik Hospital, Seoul, Korea
  • 4Department of Pediatrics, School of Medicine, Kyung Hee University, Seoul, Korea
  • 5Department of Pediatrics, Wonkwang University School of Medicine, Iksan, Korea
  • 6Department of Pediatrics, Soonchunhyang University Gumi Hospital, Gumi, Korea
  • 7Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea
  • 8Department of Pediatrics, Seoul Medical Center, Seoul, Korea
  • 9Department of Pediatrics, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea
  • 10Department of Pediatrics, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea
  • 11Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea
  • 12Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea
  • 13Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea


Allergic rhinitis (AR) is one of the most common allergic diseases characterized by stuffy nose, rhinorrhea, sneezing, and itching. Researchers have indicated an increase in the prevalence of AR and younger-age onset during the last few decades. The increasing burden of AR has caused many researchers to investigate time trends of the prevalence of AR and to identify its risk factors. The most commonly used epidemiological studies are cross-sectional ones such as the International Study of Asthma and Allergies in Childhood study and big data from National Health Insurance Service or National Health and Nutrition Examination Survey. However, these studies have many limitations including recall bias, selection bias, and deficit of objective evaluation. Furthermore, crosssectional studies cannot reflect new risk factors associated with the development of AR. New epidemiological studies will be needed to cover genetic factors, environmental changes, microbiomes, and lifestyles that are known to be risk factors for AR. Further studies will be needed to determine the prevalence, natural history, and risk factors of AR in order to advance our understanding of the pathophysiology, prevention, and management of comorbidities of AR.


Allergic rhinitis; Epidemiology; Risk factors; Natural history
Full Text Links
  • AARD
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: