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Effects of Particulate Matter on Allergic Rhinitis and Possible Mechanisms

Jung HJ, Han DH

Health impacts of particulate matter (PM) have become a global concern. PM tends to affect patients with allergic diseases, such as allergic rhinitis (AR), more severely. Many epidemiological studies have...
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Associations between pollen and allergic rhinitis in children and adolescents

Lee KS, Kim M, Kim HH, Kim HB, Rha YH, Park YM, Sung M, Sheen YH, Yum HY, Lee YJ, Chun YH, Jee HM, Choi BS, Choi SH, Park Y, ftKAoPAaRD(WGoR

Allergic rhinitis (AR) is a type of rhinitis accompanied by sensitization to allergens. One of the most clinically important allergens is pollen. Recently, due to climate change and CO 2...
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Compositional Alterations of the Nasal Microbiome and Staphylococcus aureus–Characterized Dysbiosis in the Nasal Mucosa of Patients With Allergic Rhinitis

Kim HJ, Kim JH, Han SA, Kim W

Objectives. Host–microbial commensalism can shape the innate immune response in the nasal mucosa, and the microbial characteristics of nasal mucus directly impact the mechanisms of the initial allergic responses in...
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Development of a house dust mite-induced mouse model for allergen-specific immunotherapy in allergic rhinitis

Kim SM, Kim JA, Kim HS, Yoon JS, Kim HH, Chun YH

Purpose: Allergen-specific immunotherapy (AIT) is the only known curative treatment for allergic diseases. Recently, novel immunotherapies have been developed to overcome the inconvenience and adverse reactions associated with conventional AIT....
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Smoking exposure and allergic rhinitis in children and adolescents

Choi BS, Kim HH, Kim HB, Rha YH, Park Y, Sung M, Shin YH, Yum HY, Lee KS, Lee YJ, Chun YH, Jee HM, Kim M, Park YM, Choi SH, the Rhinitis Study Group in the Korean Academy of Pediatric Allergy and Respiratory Diseases

The prevalence of allergic rhinitis in children and adolescents is constantly increasing. However, few studies exist on the relationship between smoking and allergic rhinitis. In addition to conventional cigarettes, electronic...
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Changes in levels of fractional exhaled and nasal nitric oxide after treatment in allergic rhinitis

Hong S, Jo CG, Kim H, Lee YS, Bae WY, Jung JA

Purpose: Recent studies have reported that nasal nitric oxide (NO) increases in patients with allergic rhinitis (AR) and bronchial asthma (BA), and can be used as a noninvasive test to...
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Effects of outdoor air pollution on children with allergic rhinitis

Sung M, Kim M, Kim HH, Rha YH, Park Y, Park YM, Sheen YH, Yum HY, Lee KS, Lee YJ, Chun YH, Jee HM, Choi BS, Choi SH, Kim HB, ftRSGitKAoPAaRD

The global worsening of air pollution has decreased the quality of life. Air pollutants can induce oxidative stress, epigenetic changes, and alterations to microRNA expression in the airway and skin,...
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Understanding the Mouse Model of Respiratory Allergic Diseases

Park SC

Respiratory allergic diseases, represented by allergic rhinitis and asthma, show various features due to their complex pathophysiology. Mouse models of respiratory allergic diseases replicate the characteristics of human allergic rhinitis...
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Risk factors and protective factors in pediatric patients with allergic rhinitis

Chun YH, Kim M, Kim HB, Rha YH, Park Y, Park YM, Sung M, Shin YH, Yum HY, Lee KS, Lee YJ, Jee HM, Choi BS, Choi SH, Kim HH, for the Rhinitis Study Group in the Korean Academy of Pediatric Allergy and Respiratory Diseases

Among allergic diseases of the Korean pediatric population, allergic rhinitis shows the most rapidly increasing prevalence. Its economic burden is substantial in many Asian countries including South Korea. This investigation...
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Environmental Factors Affecting Prevalence of Allergic Diseases in Elementary School Children in a Province

Kim H

Background: The aim of the study was to investigate the association between allergic diseases and their relating factors in elementary school children living in an urban area. Methods: A self-reported International...
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Dupilumab therapy in a 12-year-old boy with Kimura disease, allergic rhinitis, and IgG3 deficiency

Jo YR, Woo H, Lim DH, Kim JH

Kimura disease is characterized by painless subcutaneous masses, usually in the head and neck area as well as serum/tissue eosinophilia and elevated serum IgE levels. Various treatment methods, such as...
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Upregulation of the Vitamin D Receptor in the Nasal Mucosa of Patients With Allergic Rhinitis

Kim HG, Lee DB, Lee TH, Choi BY, Han MS, Lee SH, Kim TH

Background and Objectives: Vitamin D modulates immunity, including that of allergic diseases, and plays its roles through contact with vitamin D receptors (VDR). Recent studies have shown that patients with...
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Main epidemiological characteristics and natural history of pediatric allergic rhinitis

Kim M, Kim HH, Kim HB, Rha YH, Park Y, Sung M, Shin YH, Yum HY, Lee KS, Lee YJ, Chun YH, Jee HM, Choi BS, Choi SH, Park YM, on behalf of the Rhinitis Study Group in the Korean Academy of Pediatric Allergy and Respiratory Diseases

Allergic rhinitis (AR) is one of the most common allergic diseases characterized by stuffy nose, rhinorrhea, sneezing, and itching. Researchers have indicated an increase in the prevalence of AR and...
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Cost-Effectiveness Analysis of Immunotherapy in Patient with Allergic Rhinitis

Park JY, Kim YS, Kim JK, Cho JH

Background and Objectives All treatments must be effective and affordable. Although it is clear that immunotherapy is effective in patients with allergic rhinitis, no cost-effectiveness analysis has been conducted in...
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Current Update of Local Allergic Rhinitis

Kim SJ, Moon JW, Lee HM

Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic atopy. The symptoms, duration, severity, and comorbidities of LAR are similar to those of allergic...
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Prevalence, comorbidities, diagnosis, and treatment of nonallergic rhinitis: real-world comparison with allergic rhinitis

Yum HY, Ha EK, Shin YH, Han MY

Rhinitis is among the most common respiratory diseases in children. Nonallergic rhinitis, which involves nasal symptoms without evidence of systemic allergic inflammation or infection, is a heterogeneous entity with diverse...
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Nasal Nitric Oxide in the Upper Airway Inflammatory Diseases

Jeong JH

Exhaled nitric oxide (eNO) from the lower respiratory tract is used commonly in diagnosis and treatment monitoring of asthma patients. However, nasal nitric oxide (nNO) has not been widely used...
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The Similarity of Biomarkers Level between Direct Nasal Fluid and Nasal Lavage Fluid in Allergic Rhinitis Patients

Kim JS, Han SJ, Park JM, Kim SW, Eun YG, Kwon OE

Background and Objectives: Biomarkers of allergic rhinitis (AR) have been studied; however, little is known regarding their practical application in the diagnosis of AR. Previous studies collected samples using saline...
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Human Rhinovirus Infection Enhances the Th2 Environment in Allergic and Non-allergic Patients with Chronic Rhinosinusitis

Ko YK, Zhang YL, Wee JH, Han DH, Kim HJ, Rhee CS

Objectives. This study was conducted to determine whether patients with allergic rhinitis might be more susceptible to human rhinovirus (HRV) infection and whether the effects of infection on the elicited...
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Age Differences in Pet Sensitization by Pet Ownership

Won JY, Kwon JW, Hong SN, Lee WH

Objectives. The association between pet sensitization and pet ownership remains unclear. Therefore, we aimed to elucidate the association between pet sensitization and pet ownership by age. Methods. We retrospectively reviewed 2,883...
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