Int Neurourol J.
2021 May;25(Suppl 1):S3-7. 10.5213/inj.2142174.087.
Irreversible Bladder Remodeling Induced by Fibrosis
- Affiliations
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- 1Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea
- 2Departments of Surgery and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA
- 3Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
- 4University of California Los Angeles, Los Angeles, CA, USA
- 5Department of Urology, Ga Cheon University College of Medicine, Incheon, Korea
- 6Department of Urology, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Korea
- KMID: 2516587
- DOI: http://doi.org/10.5213/inj.2142174.087
Abstract
- Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is regarded as an important mechanism associated with bladder fibrosis. However, various risk factors and conditions contribute to the functional impairment of the bladder associated with fibrosis, and there is limited knowledge about bladder fibrosis-associated problems in the field of neurourology. Further studies are thus necessary to elucidate the underlying mechanism of bladder fibrosis and to identify effective treatment.
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