J Korean Soc Radiol.  2021 Mar;82(2):417-422. 10.3348/jksr.2020.0092.

Bilateral Breast Cancer in a Patient with Neurofibromatosis Type 1: A Case Report

• Woo SH
• Jung HK
• Kim W

• KMID: 2514735
• DOI: http://doi.org/10.3348/jksr.2020.0092

Abstract

Neurofibromatosis type 1 (NF1) is a rare neuroectodermal disease that is associated with an increased risk of malignancy. Here, we report a rare case of bilateral breast cancer in a 49-yearold woman with NF1 that presented as a microlobulated oval hypoechoic mass and a complex cystic solid mass on sonography. She underwent bilateral mastectomy. The masses were diagnosed as invasive ductal carcinoma, ductal carcinoma in situ, and a malignant peripheral nerve sheath tumor. We describe the imaging findings, including ultrasonography, CT, and ¹⁸F-fluorodeoxyglucose PET.

Keyword

Neurofibromatosis Type 1; Breast; Cancer; Malignant Peripheral Nerve Sheath Tumor; Ultrasonography