J Korean Neurosurg Soc.  2016 Nov;59(6):650-654. 10.3340/jkns.2016.59.6.650.

Giant Intrathoracic Meningocele and Breast Cancer in a Neurofibromatosis Type I Patient

• Malla HP
• Park BJ
• Koh JS
• Jo DJ

• KMID: 2417351
• DOI: http://doi.org/10.3340/jkns.2016.59.6.650

Abstract

Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of chromosome 17, one would expect concurrence of neurofibromatosis and breast cancer. However, incidence of such co-disorders is very rare in the literature. Here, the authors report a case of a 50-year-old female patient with NF-1 and concurrent cancer of the left breast, who had a huge bilobulated intrathoracic meningocele with thoracic dystrophic scoliosis, treated surgically via a posterior-only approach for the meningocele and spinal deformity in the same setting.

Keyword

Neurofibromatosis; Meningocele; Breast cancer

MeSH Terms

Arm
Breast Neoplasms*
Breast*
Chromosomes, Human, Pair 17
Congenital Abnormalities
Female
Humans
Incidence
Meningocele*
Middle Aged
Neurofibromatoses*
Neurofibromatosis 1*
Scoliosis