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Artificial Intelligence-Based Identification of Normal Chest Radiographs: A Simulation Study in a Multicenter Health Screening Cohort

Yoo H, Kim EY, Kim H, Choi YR, Kim MY, Hwang SH, Kim YJ, Cho YJ, Jin KN

Objective: This study aimed to investigate the feasibility of using artificial intelligence (AI) to identify normal chest radiography (CXR) from the worklist of radiologists in a health-screening environment. Materials and Methods:...
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Diagnostic Performance of Core Needle Biopsy for Characterizing Thyroidectomy Bed Lesions

Jeong SY, Baek JH, Chung SR, Choi YJ, Song DE, Chung KW, Kim WW, Lee JH

Objective: Thyroidectomy bed lesions frequently show suspicious ultrasound (US) features after thyroid surgery. Fine-needle aspiration (FNA) may not provide definitive pathological information about the lesions. Although core-needle biopsy (CNB) has...
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Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 Revised Edition

Kim SY, Kwak MS, Yoon SM, Jung Y, Kim JW, Boo SJ, Oh EH, Jeon SR, Nam SJ, Park SY, Park SK, Chun J, Baek DH, Choi MY, Park S, Byeon JS, Kim HK, Cho JY, Lee MS, Lee OY, TKSoGETKSoGKAftSoID

Colonoscopic polypectomy is effective in decreasing the incidence and mortality of colorectal cancer (CRC). Premalignant polyps discovered during colonoscopy are associated with the risk of metachronous advanced neoplasia. Postpolypectomy surveillance...
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Incidence and Risk Factors for Totally Implantable Venous Access Device Infections in Pediatric Patients With Cancer: A Study of 25,954 Device-Days

Lee JK, Choi YB

Background: Totally implantable venous access devices (TIVADs) are frequently used in pediatric patients with cancer owing to their multiple benefits. Despite occasional infections with TIVADs, knowledge of the incidence and...
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Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells

Park D, Lee JH, Yoon SP

Benzimidazole anthelmintic agents have been recently repurposed to overcome cancers resistant to conventional therapies. To evaluate the anti-cancer effects of benzimidazole on resistant cells, various cell death pathways were investigated...
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Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner

Choi YS, Cho HJ, Jung HJ

Gastric cancer stem cells (GCSCs) are a major cause of radioresistance and chemoresistance in gastric cancer (GC). Therefore, targeting GCSCs is regarded as a powerful strategy for the effective treatment...
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Phase I Clinical Trial of Prostate-Specific Membrane Antigen-Targeting 68 Ga-NGUL PET/CT in Healthy Volunteers and Patients with Prostate Cancer

Suh M, Ryoo HG, Kang KW, Jeong JM, Jeong CWJ, Kwak C, Cheon GJ

Objective: 68 Ga-NGUL is a novel prostate-specific membrane antigen (PSMA)-targeting tracer based on Glu-Urea-Lys derivatives conjugated to a 1,4,7-triazacyclononane-N,N’,N’’-triacetic acid (NOTA) chelator via a thiourea-type short linker. This phase I...
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Hsa_circ_0003221 facilitates the malignant development of bladder cancer cells via resulting in the upregulation of DHCR24 by targeting miR-892b

Lu P, Jiang Y, Xia Z

Purpose: This research concentrated on the biological effects and special mechanism of circ_0003221 in bladder cancer (BLCA). Materials and Methods: The level quantification by reverse transcription-quantitative polymerase chain reaction was administrated...
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Role of oral pentosan polysulfate in Bacillus Calmette–Guérin therapy in patients with non-muscle-invasive bladder cancer

Lee HY, Jung SI, Lim DG, Chung HS, Hwang EC, Kwon DD

Purpose: Intravesical Bacillus Calmette–Guérin (BCG) instillation, although an important treatment for non-muscle-invasive bladder cancer, exerts local and systemic adverse effects. Pentosan polysulfate (PPS) is a bladder mucosal protective drug that...
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Lazertinib: on the Way to Its Throne

Lee J, Hong MH, Cho BC

Lazertinib is an oral, irreversible, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that forms an irreversible covalent bond to the Cys797 residue in the ATP-binding site of...
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Factors associated with the risk of colorectal neoplasia in young adults under age 40

Kim I, Lee HH, Ko YJ, Chang HE, Cheung DY, Lee BI, Cho YS, Kim JI, Choi MG

Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal...
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CKD-581 Downregulates Wnt/β-Catenin Pathway by DACT3 Induction in Hematologic Malignancy

Kim SJ, Kim S, Choi YJ, Kim UJ, Kang KW

The present study evaluated the anti-cancer activity of histone deacetylase (HDAC)-inhibiting CKD-581 in multiple myeloma (MM) and its pharmacological mechanisms. CKD-581 potently inhibited a broad spectrum of HDAC isozymes. It...
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Comparative Study of Autophagy in Oxaliplatin-Sensitive and Resistant SNU-C5 Colon Cancer Cells

Boo SJ, Piao MJ, Kang KA, Zhen AX, Fernando PDSM, Herath HMUL, Lee SJ, Song SE, Hyun JW

Few studies have evaluated the role of autophagy in the development of oxaliplatin (OXT) resistance in colon cancer cells. In this study, we compared the role of autophagy between SNU-C5...
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Bispecific Antibody-Bound T Cells as a Novel Anticancer Immunotherapy

Cho J, Tae N, Ahn JH, Chang SY, Ko HJ, Kim DH

Chimeric antigen receptor T (CAR-T) cell therapy is one of the promising anticancer treatments. It shows a high overall response rate with complete response to blood cancer. However, there is...
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Real-World Outcomes of Gemcitabine, Cisplatin, and Nab-Paclitaxel Chemotherapy Regimen for Advanced Biliary Tract Cancer: A Propensity Score-Matched Analysis

Jung K, Park J, Jung JH, Lee JC, Kim J, Hwang JH

Background/Aims: Advanced biliary tract cancer (BTC) is associated with poor survival. A recent phase II study of triplet combination chemotherapy, including gemcitabine, cisplatin, and nanoparticle albumin-bound (nab)-paclitaxel, has shown promising...
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Effects of Reproductive Factors on Lauren Intestinal-Type Gastric Cancers in Females: A Multicenter Retrospective Study in South Korea

Jung YJ, Kim HJ, Park CH, Park SJ, Kim N

Background/Aims: Gastric cancers (GCs), particularly the Lauren intestinal type, show a male predominance. The aim of this study was to investigate the effects of reproductive factors on GCs in females,...
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Cancer Rehabilitation Fact Sheet in Korea

Yoon JA, Hong BY

Cancer rehabilitation aims to enable patients to maximize their physical, social, psychological, and vocational functions within the limits that arise during the course of the disease and its treatment. According...
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A Case of Stewart-Treves Syndrome Derived from Lymphedema Lasting for about 20 Years

Kwon HJ, Yoo DW, Park KD, Kim KH, Yoon JH

  • KMID: 2532851
  • Korean J Dermatol.
  • 2022 Aug;60(7):453-454.
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Treatment outcomes and prognostic factors in oral tongue cancer: a 20-year retrospective study at the National Cancer Center, South Korea

Kim MG, Choi YS, Youn SM, Ko JH, Oh HJ, Lee JH, Park JY, Choi SW

Objectives: This study aimed to analyze the treatment outcomes and to evaluate the clinicopathological prognostic factors of oral tongue cancer. Patients and Methods: We retrospectively analyzed treatment results and prognostic factors...
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Factors Associated with Cyto-Histological Misinterpretation of Cervical Smear according to Menopausal Status

Choi MS, Lee YJ, Lee EH, Ji YI, Park MJ

Objectives: This study aimed to compare histological outcomes between pre-menopausal and post-menopausal women with cervical cytological abnormalities and to investigate the clinical factors affecting the misinterpretation of cytology and histology. Methods:...
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