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Ann Hepatobiliary Pancreat Surg.  2020 Nov;24(4):551-556. 10.14701/ahbps.2020.24.4.551.

Neoadjuvant chemotherapy followed by total pancreatectomy with splenectomy and combined vascular resections after preoperative percutaneous transhepatic portal vein stent placement in locally advanced pancreatic cancer with portal vein total obliteration

Affiliations
  • 1Division of HBP Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea
  • 2Pancreatobiliary Cancer Center, Yonsei Cancer Center, Severance Hospital, Seoul, Korea
  • 3Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 4Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

Abstract

Pancreatic cancer is one of the most lethal malignant diseases in gastrointestinal system that only about 15-20% of the patients are potential candidates for resection at diagnostic stage. However, with the advent of neoadjuvant chemotherapy and advancement of surgical skills, patients with locally advanced pancreatic cancer (LAPC), which were deemed initially unresectable, have undergone margin negative radical resection. Here, we present a case of a patient with LAPC who was previously treated with neoadjuvant FOLFIRINOX and underwent pancreaticoduodenectomy combined with vascular resection after preoperative percutaneous transhepatic portal vein stent placement to relieve of portal vein obliteration. The patient recovered without any complication and was discharged on day 8 postoperatively.

Keyword

Locally advanced pancreatic cancer; Neoadjuvant chemotherapy; Portal vein stent
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