J Korean Soc Radiol.  2020 May;81(3):610-619. 10.3348/jksr.2020.81.3.610.

Detection of Incidental Prostate Cancer or Urothelial Carcinoma Extension in Urinary Bladder Cancer Patients by Using Multiparametric MRI: A Retrospective Study Using Prostate Imaging Reporting and Data System Version 2.0

Affiliations
  • 1Department of Radiology, Ewha Womans University Mokdong Hospital, Seoul, Korea
  • 2Departments of Radiology, Ewha Womans University College of Medicine, Seoul, Korea
  • 3Departments of Pathology, Ewha Womans University College of Medicine, Seoul, Korea

Abstract

Purpose
The study aimed to investigate the role of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) in predicting incidental prostate cancer (PCa) or urothelial carcinoma (UCa) extension in urinary bladder (UB) cancer patients.
Materials and Methods
A total of 72 UB cancer patients who underwent radical cystoprostatectomy and 3 Tesla multiparametric MRI before surgery were enrolled. PI-RADS v2 ratings were assigned by two independent radiologists. All prostate specimens were examined by a single pathologist. We compared the multiparametric MRI findings rated using PI-RADS v2 with the pathologic data.
Results
Of the 72 UB cancer patients, 29 had incidental PCa (40.3%) and 20 showed UCa extension (27.8%), with an overlap for 3 patients. With a score of 4 as the cut-off value for predicting incidental PCa, the diagnostic accuracy was 65.3%, specificity was 90.7%, and positive predictive value (PPV) was 66.7%. The diagnostic accuracy for incidental UCa extension was 47.2%, specificity was 92.3%, and PPV was 83.3%.
Conclusion
Despite the low diagnostic accuracy, the PPV and specificity were relatively high. Therefore, PI-RADS v2 scores of 1, 2, or 3 may help exclude the probability of incidental PCa or UCa extension.

Keyword

Cystectomy; Magnetic Resonance Imaging; Prostate Cancer; Urinary Bladder Cancer
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