- Diagnosis and treatment of macrocytic anemia in a perinatal common marmoset: a case report
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Kim JM, Kwak J, Lim HJ, Kim JI, Kang BC
- KMID: 2527824
- Lab Anim Res.
- 2022 Mar;38(1):57-60.
- doi: 10.1186/s42826-022-00115-6
Background: The common marmoset is widely used in current biomedical research for various research fields. We observed macrocytic anemia in a perinatal common marmoset with gradual weight loss and diarrhea.... -
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- Pulmonary vein aneurysm in a New Zealand White rabbit: a case report
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Kim JM, Woo CG, Kim SH, Jeong ES, Kim KS, Kang BC
- KMID: 2527823
- Lab Anim Res.
- 2022 Mar;38(1):53-56.
- doi: 10.1186/s42826-022-00114-7
Background: Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms.... -
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- Synergistic Promoting Effects of X-Linked Inhibitor of Apoptosis Protein and Matrix on the In Vitro Follicular Maturation of Marmoset Follicles
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Kim YY, Yun JW, Kim SW, Kim H, Kang BC, Ku SY
- KMID: 2525409
- Tissue Eng Regen Med.
- 2022 Feb;19(1):93-103.
- doi: 10.1007/s13770-021-00387-4
BACKGROUND: In Vitro follicular maturation (IVFM) of ovarian follicles is an emerging option for fertility preservation. Many paracrine factors and two-dimensional or three-dimensional (3D) environments have been used for optimization.... -
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- Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
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Yun WB, Kim JE, Lee ML, Choi JY, Park JJ, Song BR, Kang BC, Nam KT, Lee HW, Hwang DY
- KMID: 2523774
- Lab Anim Res.
- 2021 Dec;37(4):294-306.
- doi: 10.1186/s42826-021-00107-y
Background: This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including... -
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- The ‘R’ principles in laboratory animal experiments
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Lee KH, Lee DW, Kang BC
- KMID: 2510416
- Lab Anim Res.
- 2020 Dec;36(4):363-365.
- doi: 10.1186/s42826-020-00078-6
Since the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal... -
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- T1-Staging for Urinary Bladder Cancer with the Stalk and Inchworm Signs with 3.0 Tesla MRI
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Kim Dh, Kang BC, Chung J
- KMID: 2507443
- J Korean Soc Radiol.
- 2020 Sep;81(5):1194-1203.
- doi: 10.3348/jksr.2019.0149
Purpose: To evaluate the diagnostic utility of the stalk and the inchworm sign on preoperative MRI for detecting superficial bladder cancers, and to compare the diagnostic performance between the stalk... -
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- Detection of Incidental Prostate Cancer or Urothelial Carcinoma Extension in Urinary Bladder Cancer Patients by Using Multiparametric MRI: A Retrospective Study Using Prostate Imaging Reporting and Data System Version 2.0
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Yoon SE, Kang BC, Cho HH, Park S
- KMID: 2502357
- J Korean Soc Radiol.
- 2020 May;81(3):610-619.
- doi: 10.3348/jksr.2020.81.3.610
Purpose The study aimed to investigate the role of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) in predicting incidental prostate cancer (PCa) or urothelial carcinoma (UCa) extension... -
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- Changes in Cortical Auditory Evoked Potentials by Ipsilateral, Contralateral and Binaural Speech Stimulation in Normal-Hearing Adults
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Lee JY, Kang BC, Park JW, Park HJ
- KMID: 2500285
- Clin Exp Otorhinolaryngol.
- 2020 May;13(2):133-140.
- doi: 10.21053/ceo.2019.00801
Objectives. Cortical auditory evoked potentials (CAEPs) have been used to examine auditory cortical development or changes in patients with hearing loss. However, there have been no studies analyzing CAEP responses... -
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- Effect of Voxel Size on the Accuracy of Landmark Identification in Cone-Beam Computed Tomography Images
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Lee KM, Davami K, Hwang HS, Kang BC
- KMID: 2454166
- J Korean Dent Sci.
- 2019 Jun;12(1):20-28.
- doi: 10.5856/JKDS.2019.12.1.20
PURPOSE: This study was performed to evaluate the effect of voxel size on the accuracy of landmark identification in cone-beam computed tomography (CBCT) images. MATERIALS AND METHODS: CBCT images were obtained... -
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- Modulatory Effects of Single and Complex Vitamins on the In Vitro Growth of Murine Ovarian Follicles
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Kim YY, Kim YJ, Kim H, Kang BC, Ku SY, Suh CS
- KMID: 2449238
- Tissue Eng Regen Med.
- 2019 Jun;16(3):275-283.
- doi: 10.1007/s13770-019-00188-w
BACKGROUND: Vitamin is a well-known co-factor for many metabolic processes and its roles in fertility and follicular growth have been studied. Vitamin supplementation is frequently achieved by daily ingestion in... -
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- CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice
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Kim JI, Park JS, Kwak J, Lim HJ, Ryu SK, Kwon E, Han KM, Nam KT, Lee HW, Kang BC
- KMID: 2459309
- Lab Anim Res.
- 2018 Dec;34(4):302-310.
- doi: 10.5625/lar.2018.34.4.302
CD47 (integrin-associated protein), a multi-spanning transmembrane protein expressed in all cells including red blood cells (RBCs) and leukocytes, interacts with signal regulatory protein α (SIRPα) on macrophages and thereby inhibits... -
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- CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model
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Lee H, Kim JI, Park JS, Roh JI, Lee J, Kang BC, Lee HW
- KMID: 2459306
- Lab Anim Res.
- 2018 Dec;34(4):279-287.
- doi: 10.5625/lar.2018.34.4.279
Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various... -
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- CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice
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Kim JI, Park JS, Kim H, Ryu SK, Kwak J, Kwon E, Yun JW, Nam KT, Lee HW, Kang BC
- KMID: 2459292
- Lab Anim Res.
- 2018 Dec;34(4):166-175.
- doi: 10.5625/lar.2018.34.4.166
Recombination activating gene-2 (RAG-2) plays a crucial role in the development of lymphocytes by mediating recombination of T cell receptors and immunoglobulins, and loss of RAG-2 causes severe combined immunodeficiency... -
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- Successful development of squamous cell carcinoma and hyperplasia in RGEN-mediated p27 KO mice after the treatment of DMBA and TPA
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Choi JY, Yun WB, Kim JE, Lee MR, Park JJ, Song BR, Kim HR, Park JW, Kang MJ, Kang BC, Lee HW, Hwang DY
- KMID: 2420824
- Lab Anim Res.
- 2018 Sep;34(3):118-125.
- doi: 10.5625/lar.2018.34.3.118
To evaluate the carcinogenicity of p27 knockout (KO) mice with RNA-guided endonuclease (RGENs)-mediated p27 mutant exon I gene (IΔ), alterations in the carcinogenic phenotypes including tumor spectrum, tumor suppressor proteins,... -
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- The Use of Normal Stem Cells and Cancer Stem Cells for Potential Anti-Cancer Therapeutic Strategy
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Han SW, Kim YY, Kang WJ, Kim HC, Ku SY, Kang BC, Yun JW
- KMID: 2418094
- Tissue Eng Regen Med.
- 2018 Aug;15(4):365-380.
- doi: 10.1007/s13770-018-0128-8
BACKGROUND: Despite recent advance in conventional cancer therapies including surgery, radiotherapy, chemotherapy, and immunotherapy to reduce tumor size, unfortunately cancer mortality and metastatic cancer incidence remain high. Along with a... -
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- Gold thread implantation promotes hair growth in human and mice
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Kim JH, Cho EY, Kwon E, Kim WH, Park JS, Lee YS, Yun JW, Kang BC
- KMID: 2402265
- Lab Anim Res.
- 2017 Dec;33(4):291-297.
- doi: 10.5625/lar.2017.33.4.291
Thread-embedding therapy has been widely applied for cosmetic purposes such as wrinkle reduction and skin tightening. Particularly, gold thread was reported to support connective tissue regeneration, but, its role in... -
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- Value of imaging study in predicting pelvic lymph node metastases of uterine cervical cancer
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Jung W, Park KR, Lee KJ, Kim K, Lee J, Jeong S, Kim YJ, Kim J, Yoon HJ, Kang BC, Koo HS, Sung SH, Cho MS, Park S
- KMID: 2401788
- Radiat Oncol J.
- 2017 Dec;35(4):340-348.
- doi: 10.3857/roj.2017.00206
PURPOSE: To evaluate the diagnostic accuracy of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) in predicting pelvic lymph node (LN) metastases in patients with... -
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- Evaluation of in vitro and in vivo genotoxicity of Angelica acutiloba in a standard battery of assays
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Yun JW, Kim YS, Kwon E, Kim SH, You JR, Kim HH, Che JH, Kang BC
- KMID: 2391096
- Lab Anim Res.
- 2017 Sep;33(3):231-236.
- doi: 10.5625/lar.2017.33.3.231
Among three representative species of Angelica found in Asian countries, including Korea, China, and Japan, Angelica acutiloba (AA) has been used as traditional herbal medicine with antitumor, anti-inflammatory, anti-obesity, and... -
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- Preclinical safety assessment of Angelica acutiloba using a 13-week repeated dose oral toxicity study in rats
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Yun JW, Kwon E, Kim SH, You JR, Kim YS, Park IA, Kim HH, Che JH, Kang BC
- KMID: 2391095
- Lab Anim Res.
- 2017 Sep;33(3):223-230.
- doi: 10.5625/lar.2017.33.3.223
Angelica acutiloba (AA), a Japanese species of Danggui, has been used worldwide as a traditional herbal medicine with several bioactivities including anti-diabetic, anti-allergic, anti-inflammatory, anti-tumor, and anti-obesity. However, there is... -
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- Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model
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Choi B, Yu J, Han TS, Kim YK, Hur K, Kang BC, Kim WH, Kim DY, Lee HJ, Kim VN, Yang HK
- KMID: 2367512
- Cancer Res Treat.
- 2017 Jan;49(1):150-160.
- doi: 10.4143/crt.2015.462
PURPOSE: MicroRNAs (miRNAs) regulate various cellular functions, including development, cell proliferation, apoptosis, and tumorigenesis. Different signatures associated with various tissue types, diagnosis, progression, prognosis, staging, and treatment response have been... -
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