Korean J Urol Oncol.  2019 Dec;17(3):190-194. 10.22465/kjuo.2019.17.3.190.

Clinical Features of Disseminated Intravascular Coagulation With Spontaneous Ruptured Primary Renal Angiosarcoma

Affiliations
  • 1Department of Urology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. sydad@hanmail.net
  • 2Department of Radiology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.

Abstract

Angiosarcoma is a rare malignant tumor accounting for less than 2% of all soft tissue sarcomas. Primary angiosarcoma of the kidney is an extremely rare but a highly aggressive tumor with poor prognosis. Patients frequently have symptoms of flank pain, hematuria, or abdominal mass. Surgery is the mainstay of treatment followed by radiation with or without chemotherapy. We describe the case of a 61-year-old man with rupture of a primary renal angiosarcoma with clinical features of disseminated intravascular coagulation (DIC). The patient underwent radical nephrectomy, and DIC including uncontrolled thrombocytopenia was resolved after the operation. We suggest that renal angiosarcoma is a cause of extensive retroperitoneal hematomas with clinical features of DIC.

Keyword

Angiosarcoma; Kidney; Thrombocytopenia; Disseminated intravascular coagulation

MeSH Terms

Dacarbazine
Disseminated Intravascular Coagulation*
Drug Therapy
Flank Pain
Hemangiosarcoma*
Hematoma
Hematuria
Humans
Kidney
Middle Aged
Nephrectomy
Prognosis
Rupture
Sarcoma
Thrombocytopenia
Dacarbazine
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