Kosin Med J.  2019 Dec;34(2):126-137. 10.7180/kmj.2019.34.2.126.

Tree Pollen Sensitization and Cross-Reaction of Children with Allergic Rhinitis or Asthma

Affiliations
  • 1Department of Pediatrics, Busan St. Mary's Hospital, Busan, Korea. hyh190@naver.com

Abstract


OBJECTIVES
Tree pollen causes allergic rhinitis and asthma. We investigated children who diagnosed as rhinitis or asthma, living in Busan, for tree allergen sensitization, component allergen, oral allergy syndrome, and the relationship between pollen counts and allergen sensitization.
METHODS
Pollen were collected in Busan, from January 1 to December 31, 2017, using a Rotorod sampler and enumerated using a microscope. We conducted a study of children with rhinitis or asthma at Busan St. Mary's Hospital in 2017, administered an ISAAC questionnaire, and an oral allergy syndrome survey. Serum specific Ig E tests were performed.
RESULTS
Among the 57 patients, the mean age was 9.3 years. The pollen counts in decreasing order were as follows: pine, alder, oak, juniper, beech, ginkgo, and birch. For sensitization, birch and alder 35.1%, Japanese cedar 19.3%, juniper 17.5%, pine 10.5%, and Japanese cypress 8.2%. The component Ig E was tested in 27 patients. Bet v 1 had a high correlation with birch, alder, and peach. Bet v 2 showed a statistically significant correlation with all tree pollen except cypress. Bet v 4 did not have any apparent correlation. Bet v 6 had the same pattern as Bet v 2, but correlation coefficient was higher than that of Bet v 2. Oral allergy syndrome was noted in 7 patients, including peach, peanut, apple, tomato, kiwi, and sesame.
CONCLUSIONS
Alder and juniper are clinically important tree pollens in Busan. These pollens cause sensitization to birch and Japanese cedar by cross-reaction.

Keyword

Allergy; Busan; Pollen

MeSH Terms

Alnus
Arachis
Asian Continental Ancestry Group
Asthma*
Betula
Busan
Child*
Cryptomeria
Cupressus
Fagus
Ginkgo biloba
Humans
Hypersensitivity
Juniperus
Lycopersicon esculentum
Pollen*
Prunus persica
Rhinitis
Rhinitis, Allergic*
Sesamum
Trees*

Figure

  • Fig. 1 Monthly pollen in Busan (2017)

  • Fig. 2 The sensitization rates of the patients

  • Fig. 3 The correlation of specific Ig E between alder and birch (A), juniper and Japanese cedar (B)


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