J Korean Orthop Assoc.  1978 Sep;13(3):285-297. 10.4055/jkoa.1978.13.3.285.

A Clinical Study on Pyogenic Osteomyelitis of 725 Cases During Past 21 Years

Abstract

Pyogenic osteomyelitis is a difficult and complex disease. The wide spectrum of manifestation of disease related to the site of involvement, the infecting organism, the initiating event and the acute or chronic course of the illness are important in determining the success or failure of treatment. Seven hundred and twenty-five cases of pyogenic osteomyelitis were studied in the Department of Orthopedic Surgery, Seoul National University Hospital for 21 years from December 1956 to December 1977. The results were as follows: 1. During past 21 years, total number of admitted patients were 10,456. Among them, number of patients of pyogenic osteomyelitis were 725. 2. Femur and tibia were frequently involved (64%), and humerus, spine, pelvis, in that orders. 3. Sex ratio was 2.4: 1. Age distribution showed the group between 6 and 15 years old was 58% in acute course, and the group between 16 and 25 years old was 34% in chronic course. 4. Duration of disease was average 7.4 days in acute and 46.8 months in chronic osteomyelitis. 5. Most of acute osteomyelitis had pyrexia (av. 38.3C), but in chronic osteomyelitis body temperature was mostly within normal limit. 6. Erythrocyte sedimentation rate was definitely increased in 81% of male, in 58% of female. 7. The causative organism was mostly coaulase (+) staphylococcus aureus (73%), but there was tendency to increase Gram (−) bacilli infection. 8. One kundred and six patients had been complicated with draining sinus, joint stiffness, and pathologic fracture. 9. Various treatments had been carried out case by case. Author considered the best method of treatment was ealry decompression and antibiotics in acute osteomyelitis, and saucerization with closed irrigation in chronic osteomyelitis.


MeSH Terms

Age Distribution
Anti-Bacterial Agents
Blood Sedimentation
Body Temperature
Clinical Study*
Decompression
Female
Femur
Fever
Fractures, Spontaneous
Humans
Humerus
Joints
Male
Methods
Orthopedics
Osteomyelitis*
Pelvis
Seoul
Sex Ratio
Spine
Staphylococcus aureus
Tibia
Anti-Bacterial Agents
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