Ann Clin Neurophysiol.  2019 Jul;21(2):102-104. 10.14253/acn.2019.21.2.102.

Transient global amnesia associated with multiple lesions in the corpus callosum and hippocampus

Affiliations
  • 1Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. koodaelim@gmail.com

Abstract

Transient global amnesia is a syndrome of temporary loss of short-term memory and is not accompanied by any other neurological deficit. Diffusion-weighted imaging is useful to improve the diagnostic accuracy of transient global amnesia. We report a 68-year-old woman with multiple lesions on diffusion-weighted imaging in the right corpus callosum and left hippocampus. To the best of our knowledge, this is the first case of a diffusion-weighted imaging lesion in the body portion of the corpus callosum.

Keyword

Transient global amnesia; Stroke; Magnetic resonance imaging

MeSH Terms

Aged
Amnesia, Transient Global*
Corpus Callosum*
Female
Hippocampus*
Humans
Magnetic Resonance Imaging
Memory, Short-Term
Stroke

Figure

  • Fig. 1 Hyperintensities on a magnetic resonance imaging scan in a patient with recurrent transient global amnesia (TGA) episodes. In the first TGA episode, diffusion-weighted imaging (DWI) revealed hyperintense lesions in (A, arrow) the left hippocampus and (B, arrow) the right corpus callosum. In the second TGA episode, (C, arrows) hyperintense lesions on DWI and (D, arrows) apparent-diffusion-coefficient-matched low signal intensities were located in the left hippocampus.


Reference

1. Hodges JR, Warlow CP. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry. 1990; 53:834–843.
Article
2. Sedlaczek O, Hirsch JG, Grips E, Peters CN, Gass A, Wöhrle J, et al. Detection of delayed focal MR changes in the lateral hippocampus in transient global amnesia. Neurology. 2004; 62:2165–2170.
Article
3. Ay H, Furie KL, Yamada K, Koroshetz WJ. Diffusion-weighted MRI characterizes the ischemic lesion in transient global amnesia. Neurology. 1998; 51:901–903.
Article
4. Saito K, Kimura K, Minematsu K, Shiraishi A, Nakajima M. Transient global amnesia associated with an acute infarction in the retrosplenium of the corpus callosum. J Neurol Sci. 2003; 210:95–97.
Article
5. Valenstein E, Bowers D, Verfaellie M, Heilman KM, Day A, Watson RT. Retrosplenial amnesia. Brain. 1987; 110(Pt 6):1631–1646.
Article
6. Sander K, Sander D. New insights into transient global amnesia: recent imaging and clinical findings. Lancet Neurol. 2005; 4:437–444.
Article
7. Fisher M, Albers GW. Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke. Neurology. 1999; 52:1750–1756.
Article
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