- Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
-
Cho KO, Jeong KH, Cha JH, Kim SY
- KMID: 2466572
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):81-88.
- doi: 10.4196/kjpp.2020.24.1.81
Regulator of calcineurin 1 (RCAN1) can be induced by an intracellular calcium increase and oxidative stress, which are characteristic features of temporal lobe epilepsy. Thus, we investigated the spatiotemporal expression... -
- CITED
-
- Close
- SHARE
-
- Close
- Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
-
Kwon HJ, Kim W, Jung HY, Kang MS, Kim JW, Hahn KR, Yoo DY, Yoon YS, Hwang IK, Kim DW
- KMID: 2470012
- Lab Anim Res.
- 2019 Dec;35(4):154-164.
- doi: 10.1186/s42826-019-0020-2
In the present study, we investigated the effects of heat shock protein 70 (HSP70) on novel object recognition, cell proliferation, and neuroblast differentiation in the hippocampus. To facilitate penetration into... -
- CITED
-
- Close
- SHARE
-
- Close
- Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus
-
Lee TK, Park YE, Park CW, Kim B, Lee JC, Park JH, Lee HA, Won MH, Ahn JH
- KMID: 2470010
- Lab Anim Res.
- 2019 Oct;35(3):140-147.
- doi: 10.1186/s42826-019-0022-0
P53 and its family member p63 play important roles in cellular senescence and organismal aging. In this study, p53 and p63 immunoreactivity were examined in the hippocampus of young, adult... -
- CITED
-
- Close
- SHARE
-
- Close
- RbAp48 expression and neuronal damage in the gerbil hippocampus following 5 min of transient ischemia
-
Park JH, Lee TK, Kim DW, Park CW, Park YE, Kim B, Lee JC, Lee HA, Won MH, Ahn JH
- KMID: 2470111
- Lab Anim Res.
- 2019 Aug;35(2):78-85.
- doi: 10.1186/s42826-019-0011-3
Histone-binding protein RbAp48 has been known to be involved in histone acetylation, and epigenetic alterations of histone modifications are closely associated with the pathogenesis of ischemic reperfusion injury. In the... -
- CITED
-
- Close
- SHARE
-
- Close
- Transient global amnesia associated with multiple lesions in the corpus callosum and hippocampus
-
Kim JA, Min YG, Koo DL
- KMID: 2454732
- Ann Clin Neurophysiol.
- 2019 Jul;21(2):102-104.
- doi: 10.14253/acn.2019.21.2.102
Transient global amnesia is a syndrome of temporary loss of short-term memory and is not accompanied by any other neurological deficit. Diffusion-weighted imaging is useful to improve the diagnostic accuracy... -
- CITED
-
- Close
- SHARE
-
- Close
- Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus
-
Shin MS, Kim TW, Park SS, Ko IG, Kim CJ, Kim M, Roh SY, Kim KT, Kim KH
- KMID: 2452559
- Int Neurourol J.
- 2019 Jun;23(2):116-124.
- doi: 10.5213/inj.1938103.052
PURPOSE: Goserelin is a drug used for chemical castration. In a rat model, we investigated whether surgical and chemical castration affected memory ability through the protein kinase A (PKA)/cyclic adenosine... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes of myelin basic protein in the hippocampus of an animal model of type 2 diabetes
-
Nam SM, Kwon HJ, Kim W, Kim JW, Hahn KR, Jung HY, Kim DW, Yoo DY, Seong JK, Hwang IK, Yoon YS
- KMID: 2459293
- Lab Anim Res.
- 2018 Dec;34(4):176-184.
- doi: 10.5625/lar.2018.34.4.176
In this study, we observed chronological changes in the immunoreactivity and expression level of myelin basic protein (MBP), one of the most abundant proteins in the central nervous system, in... -
- CITED
-
- Close
- SHARE
-
- Close
- Brain consequences of acute kidney injury: Focusing on the hippocampus
-
Malek M
- KMID: 2447176
- Kidney Res Clin Pract.
- 2018 Dec;37(4):315-322.
- doi: 10.23876/j.krcp.18.0056
The high mortality rates associated with acute kidney injury are mainly due to extra-renal complications that occur following distant-organ involvement. Damage to these organs, which is commonly referred to as... -
- CITED
-
- Close
- SHARE
-
- Close
- Chronic Cerebral Hypoperfusion Induces Alterations of Matrix Metalloproteinase-9 and Angiopoietin-2 Levels in the Rat Hippocampus
-
Kim MS, Choi BR, Lee YW, Kim DH, Han YS, Jeon WK, Han JS
- KMID: 2419339
- Exp Neurobiol.
- 2018 Aug;27(4):299-308.
- doi: 10.5607/en.2018.27.4.299
Angiogenic factors contribute to cerebral angiogenesis following cerebral hypoperfusion, and understanding these temporal changes is essential to developing effective treatments. The present study examined temporal alterations in angiogenesis-related matrix metalloproteinase-9... -
- CITED
-
- Close
- SHARE
-
- Close
- Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus
-
Chun H, An H, Lim J, Woo J, Lee J, Ryu H, Lee CJ
- KMID: 2416243
- Exp Neurobiol.
- 2018 Jun;27(3):155-170.
- doi: 10.5607/en.2018.27.3.155
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their... -
- CITED
-
- Close
- SHARE
-
- Close
- Exposure to 835 MHz RF-EMF decreases the expression of calcium channels, inhibits apoptosis, but induces autophagy in the mouse hippocampus
-
Kim JH, Sohn UD, Kim HG, Kim HR
- KMID: 2410092
- Korean J Physiol Pharmacol.
- 2018 May;22(3):277-289.
- doi: 10.4196/kjpp.2018.22.3.277
The exponential increase in the use of mobile communication has triggered public concerns about the potential adverse effects of radiofrequency electromagnetic fields (RF-EMF) emitted by mobile phones on the central... -
- CITED
-
- Close
- SHARE
-
- Close
- Dendropanax morbifera Léveille extract ameliorates D-galactose-induced memory deficits by decreasing inflammatory responses in the hippocampus
-
Lee KY, Jung HY, Yoo DY, Kim W, Kim JW, Kwon HJ, Kim DW, Yoon YS, Hwang IK, Choi JH
- KMID: 2402264
- Lab Anim Res.
- 2017 Dec;33(4):283-290.
- doi: 10.5625/lar.2017.33.4.283
In the present study, we examined the effects of Dendropanax morbifera Léveille leaf extract (DML) on D-galactose-induced morphological changes in microglia and cytokines, including pro-inflammatory cytokines (interleukin [IL]-1β, IL-6, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Beneficial Effects of Silibinin Against Kainic Acid-induced Neurotoxicity in the Hippocampus in vivo
-
Kim S, Jung UJ, Oh YS, Jeon MT, Kim HJ, Shin WH, Hong J, Kim SR
- KMID: 2398431
- Exp Neurobiol.
- 2017 Oct;26(5):266-277.
- doi: 10.5607/en.2017.26.5.266
Silibinin, an active constituent of silymarin extracted from milk thistle, has been previously reported to confer protection to the adult brain against neurodegeneration. However, its effects against epileptic seizures have... -
- CITED
-
- Close
- SHARE
-
- Close
- Functional Connectivity of the Hippocampus in Early- and vs. Late-Onset Alzheimer's Disease
-
Park KH, Noh Y, Choi EJ, Kim H, Chun S, Son YD
- KMID: 2392135
- J Clin Neurol.
- 2017 Oct;13(4):387-393.
- doi: 10.3988/jcn.2017.13.4.387
BACKGROUND AND PURPOSE: Early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD) have different clinical and neuroimaging characteristics, but memory decline is usually present in both types. However, there have... -
- CITED
-
- Close
- SHARE
-
- Close
- Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils
-
Ahn JH, Lee TK, Park JH, Cho JH, Kim IH, Lee JC, Hong S, Jeon YH, Kang IJ, Lee YJ, Won MH, Lee CH
- KMID: 2391097
- Lab Anim Res.
- 2017 Sep;33(3):237-243.
- doi: 10.5625/lar.2017.33.3.237
Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus,... -
- CITED
-
- Close
- SHARE
-
- Close
- Reduction of long-term potentiation at Schaffer collateral-CA1 synapses in the rat hippocampus at the acute stage of vestibular compensation
-
Lee GW, Kim JH, Kim MS
- KMID: 2384456
- Korean J Physiol Pharmacol.
- 2017 Jul;21(4):423-428.
- doi: 10.4196/kjpp.2017.21.4.423
Vestibular compensation is a recovery process from vestibular symptoms over time after unilateral loss of peripheral vestibular end organs. The aim of the present study was to observe time-dependent changes... -
- CITED
-
- Close
- SHARE
-
- Close
- Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats
-
Park JH, Ko IG, Kim SE, Jin JJ, Hwang L, Kim CJ, Yoon SH, Hong J, Chung JY, Lee DW
- KMID: 2378437
- Int Neurourol J.
- 2017 Apr;21(Suppl 1):S39-S47.
- doi: 10.5213/inj.1734884.442
PURPOSE: Dexmedetomidine, an α2-adrenergic agonist, provides sedative and analgesic effects without significant respiratory depression. Dexmedetomidine has been suggested to have an antiapoptotic effect in response to various brain insults. We... -
- CITED
-
- Close
- SHARE
-
- Close
- Morphological and Microstructural Changes of the Hippocampus in Early MCI: A Study Utilizing the Alzheimer's Disease Neuroimaging Initiative Database
-
Lee P, Ryoo H, Park J, Jeong Y, Alzheimer's Disease Neuroimaging Initiative
- KMID: 2376015
- J Clin Neurol.
- 2017 Apr;13(2):144-154.
- doi: 10.3988/jcn.2017.13.2.144
BACKGROUND AND PURPOSE: With the aim of facilitating the early detection of Alzheimer's disease, the Alzheimer's Disease Neuroimaging Initiative proposed two stages based on the memory performance: early mild cognitive... -
- CITED
-
- Close
- SHARE
-
- Close
- Astrocytic Expression of CTMP Following an Excitotoxic Lesion in the Mouse Hippocampus
-
Shin N, Yi MH, Kim S, Baek H, Triantafillu UL, Park J, Kim DW
- KMID: 2368652
- Exp Neurobiol.
- 2017 Feb;26(1):25-32.
- doi: 10.5607/en.2017.26.1.25
Akt (also known as protein kinase B, PKB) has been seen to play a role in astrocyte activation of neuroprotection; however, the underlying mechanism on deregulation of Akt signaling in... -
- CITED
-
- Close
- SHARE
-
- Close
- Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical, Bacopa Monnieri
-
Hazra S, Kumar S, Saha GK, Mondal AC
- KMID: 2365015
- Psychiatry Investig.
- 2017 Jan;14(1):74-80.
- doi: 10.4306/pi.2017.14.1.74
OBJECTIVE: The aims of the present study were to explore the behavioural effects and to understand the possible mode of action of Bacopa monnieri extract (BME) on chronic unpredictable stress... -
- CITED
-
- Close
- SHARE
-
- Close
