Asian Spine J.  2019 Jun;13(3):519-526. 10.31616/asj.2018.0096.

Etiology of Adolescent Idiopathic Scoliosis: A Literature Review

• Kikanloo S
• Tarpada SP
• Cho W

• KMID: 2449808
• DOI: http://doi.org/10.31616/asj.2018.0096

Abstract

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.

Keyword

Adolescent; Scoliosis; Adolescent idiopathic scoliosis; Etiology; Cobb angle; Review

MeSH Terms

Adolescent*
Braces
Humans
Scoliosis*
Spinal Curvatures