Ann Dermatol.  2019 Apr;31(2):213-216. 10.5021/ad.2019.31.2.213.

Congenital Dermal Melanocytosis on the Foot: A Case Report and Review of the Literature

• Cho SI
• Moon J
• Jo G
• Lee C
• Mun JH

• KMID: 2439069
• DOI: http://doi.org/10.5021/ad.2019.31.2.213

Abstract

Dermal melanocytosis is a common pigmented skin disease, characterized by an increased number of ectopic melanocytes in the dermis. Rare variants of dermal melanocytosis that do not belong to these four typical groups-nevus of Ota, nevus of Ito, blue nevus, and Mongolian spots-are called dermal melanocyte hamartoma, or congenital dermal melanocytosis (CDM) as it mostly appears from birth. We report a case of CDM on the foot of a young woman with a literature review of previously reported cases of CDM.

Keyword

Congenital; Dermis; Melanocytes; Nevus; blue; Pigmentation disorders

MeSH Terms

Dermis
Female
Foot*
Hamartoma
Humans
Melanocytes
Nevus
Nevus, Blue
Parturition
Pigmentation Disorders
Skin Diseases

Figure

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  Fig. 1 (A) Mottled, confluent, blue-gray macules surrounding darker patches on the right dorsum of the foot. (B) Steel blue or gray structureless area surrounded by mottled brown globules on dermoscopy.

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  Fig. 2 (A~C) Increased and scattered pigmented melanocytes without nest formation throughout the dermis. Scattered and elongated melanocytes among collagen bundles without certain orientation (H&E; A: ×100, B: ×200, C: ×400). (D) Melanocytes were positively stained for Melan-A (MART-1, ×200).

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