Clin Endosc.  2018 Jul;51(4):362-367. 10.5946/ce.2017.177.

Accuracy of Endoscopic Diagnosis for Mild Atrophic Gastritis Infected with Helicobacter pylori

• Okamura T
• Iwaya Y
• Kitahara K
• Suga T
• Tanaka E

• KMID: 2419708
• DOI: http://doi.org/10.5946/ce.2017.177

Abstract

BACKGROUND/AIMS
This study examined the accuracy of endoscopic evaluation for determining the Helicobacter pylori infection status in patients with mild atrophy who might not exhibit characteristic endoscopic findings.
METHODS
Forty endoscopists determined the H. pylori infection status of 50 randomly presented H. pylori-positive and H. pylori-negative cases on the basis of a list of established findings.
RESULTS
The median clinical endoscopy experience was 7 years (range, 1-35 years), including 22 board-certified endoscopists (55%) of the Japan Gastroenterological Endoscopy Society. The mean accuracy rate of endoscopic diagnosis was 67% and was unrelated to experience status (experienced vs. trainee: 69% vs. 65%, p=0.089) and total years of experience (R 2 =0.022). The most frequently selected endoscopic findings were regular arrangement of collecting venules (59%), atrophy (45%), and red streak (22%), which had fair accuracy rates of 67%, 65%, and 73%, respectively. By contrast, the accuracy rates of nodularity (89%) and mucosal swelling (77%) were highest. The 20 endoscopists who more frequently identified these findings diagnosed H. pylori infection significantly more accurately than did the other endoscopists (71% vs. 64%, p=0.008).
CONCLUSIONS
Careful attention to nodularity and mucosal swelling in patients with mild atrophy may enhance diagnosis, enable prompt treatment, and avoid possible long-term carcinogenesis.

Keyword

Diagnostic accuracy; Endoscopic diagnosis; Helicobacter pylori; Mild atrophy

MeSH Terms

Atrophy
Carcinogenesis
Diagnosis*
Endoscopy
Gastritis, Atrophic*
Helicobacter pylori*
Helicobacter*
Humans
Japan
Venules

Figure

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  Fig. 1. Helicobacter pylori-positive case (30-year-old man). (A) Antrum, (B) angulus, (C) lesser curvature of the lower body, (D) greater curvature of the lower body, (E) greater curvature of the upper body, and (F) cardia.

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  Fig. 2. Correlation between accuracy rate and endoscopy experience.

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  Fig. 3. Endoscopic features. (A) Antrum with nodularity and (B) greater curvature of the lower body with mucosal swelling.

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  Fig. 4. Accuracy rate according to the frequency of selecting nodularity or mucosal swelling.

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