Neurospine.  2018 Mar;15(1):33-41. 10.14245/ns.1836084.042.

Ossification of the Posterior Longitudinal Ligament in Cervical Spine: Prevalence, Management, and Prognosis

Affiliations
  • 1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan. wchuang@vghtpe.gov.tw
  • 2School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • 3Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Abstract

Ossification of the posterior longitudinal ligament (OPLL) in the cervical spine and related neurological complications are not uncommon in East Asian countries. The estimated prevalence of cervical OPLL-related hospitalization is 7.7 per 100,000 person-years in Taiwan, and higher incidence rates have been observed in elderly and male patients. Although cervical OPLL is frequently insidious, it can eventually cause myelopathy and predispose patients to spinal cord injury (SCI). There are multiple options for managing cervical OPLL, ranging from observation to many kinds of surgical procedures, including posterior laminoplasty, laminectomy with or without fusion, anterior corpectomy with or without instrumentation, and circumferential decompression and fusion. None of these surgical approaches is free of complications. However, to date, there is still a lack of consensus regarding the choice of the surgical approach and the timing of surgical intervention. Cervical SCI and related neurological disabilities are more likely to occur in OPLL patients, who should therefore be cautioned regarding the possibility of a subsequent SCI if treated without surgery. This article aimed to review the prevalence, management strategies, and prognosis of cervical OPLL.

Keyword

Ossification of posterior longitudinal ligament; Cervical; Prevalence; Spinal cord injury

MeSH Terms

Aged
Asian Continental Ancestry Group
Consensus
Decompression
Hospitalization
Humans
Incidence
Laminectomy
Laminoplasty
Longitudinal Ligaments*
Male
Ossification of Posterior Longitudinal Ligament
Prevalence*
Prognosis*
Spinal Cord Diseases
Spinal Cord Injuries
Spine*
Taiwan
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