J Korean Soc Radiol.  2018 Jun;78(6):371-379. 10.3348/jksr.2018.78.6.371.

Quantitative Computed Tomography Assessment of Respiratory Muscles in Male Patients Diagnosed with Emphysema

Affiliations
  • 1Department of Radiology, Dongnam Institute of Radiological & Medical Sciences, Busan, Korea.
  • 2Department of Radiology, Dong-A University Hospital, Busan, Korea. gnlee@dau.ac.kr
  • 3Department of Radiology, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea.

Abstract

PURPOSE
The aim of this study was to accurately evaluate the significance and correlation between the clinical severity and the morphologic feature of respiratory muscles in patients with emphysema as noted using computed tomography (CT).
MATERIALS AND METHODS
The cross sectional area (CSA) and attenuation of respiratory muscles in the patients with emphysema (n = 71) were subsequently retrospectively reviewed. The clinical severity for the patients was determined by the value of the actual forced expiratory volume in 1 second/forced vital capacity at the pulmonary function test (PFT). The correlation between the CT measurements with visual assessment of emphysema (VAE), and the PFT values were completed and recorded. The multiple linear regression analysis of each CT measurement on the VAE and PFT values was used to determine the most affective parameters among the recorded and identified CT measurements.
RESULTS
The CSA of the pectoralis major (p = 0.002) and subsequently the serratus anterior (p = 0.011) were found to be lower in patients with emphysema than as compared to those in the control group. The CSA and the attenuation of respiratory muscles remained significant for its relation for the VAE and PFT values. As noted, both the VAE and PFT values were mostly contributed by the CSA and attenuation of serratus anterior and attenuation of diaphragm crus among all respiratory muscles.
CONCLUSION
The CT measurement of the patient's respiratory muscles may reflect clinical and visual severity in the patients with emphysema.


MeSH Terms

Diaphragm
Emphysema*
Forced Expiratory Volume
Humans
Linear Models
Male*
Multidetector Computed Tomography
Pulmonary Disease, Chronic Obstructive
Respiratory Function Tests
Respiratory Muscles*
Retrospective Studies
Vital Capacity
Full Text Links
  • JKSR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error