J Korean Orthop Assoc.  2018 Feb;53(1):58-65. 10.4055/jkoa.2018.53.1.58.

Diagnosis and Treatment of Bizarre Parosteal Osteochondromatous Proliferation

  • 1Department of Orthopedic Surgery, Yeungnam University Medical Center, Daegu, Korea. karaz101@ynu.ac.kr


There have been a few reports of bizarre parosteal osteochondromatous proliferation (BPOP) in Korea to date. The purpose
of this study was to investigate the etiology, diagnosis, treatment, and prognosis of BPOP and to report the clinical outcomes from a single institution.
Between 1999 and 2016, six patients who were diagnosed and treated operatively at Yeungnam University Medical Center were reviewed retrospectively. The analysis was performed using medical records, simple radiographs, magnetic resonance imaging (MRI), and pathology results, based on clinical and oncological results. All patients underwent surgical treatment for complete resection. We also analyzed one patient who was initially diagnosed with BPOP, showing different clinical features during the follow-up period.
The age of patients ranged from 17 to 60 years. All patients did not show a history of trauma. All patients showed localized edema on the tumor lesion, and three patients also showed tenderness. The tumor lesions were distributed to the femur, tibia, and humerus. All patients underwent marginal resection or wide resection. The mean follow-up period was 50.3 months. There was a malignant change in one patient, but no recurrence or metastasis.
In this study, there was no difference in the incidence of BPOP in accordance with sex. Moreover, there was no significant relationship between trauma and onset of BPOP. Unlike previous reports, no recurrence occurred after complete resection. If BPOP is diagnosed, it is necessary to consider the possibility of malignant change and distinguish it from other malignant tumors.


bizarre parosteal osteochondromatous proliferation; Nora's lesion
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