Korean J Med.  2017 Dec;92(6):499-505. 10.3904/kjm.2017.92.6.499.

New Classification Criteria for Primary Sjögren's Syndrome and Salivary Gland Ultrasonography

• Lee KA
• Kim HR
• Lee SH

• KMID: 2400913
• DOI: http://doi.org/10.3904/kjm.2017.92.6.499

Abstract

Primary Sjögren's syndrome (pSS) is a chronic autoimmune inflammatory disorder characterized by lymphocytic infiltration of exocrine organs. Since 1965, several sets of classification criteria for pSS have been proposed by single experts or groups of multidisciplinary specialists. In 2002, the American-European Consensus Group proposed new classification criteria, which have been widely used in both clinical trials and routine clinical practice. In 2012, updated classification criteria were approved by the American College of Rheumatology (ACR). The existence of two different sets of criteria emphasized the need for an international consensus. Using methods consistent with those employed to develop recent ACR/European League Against Rheumatism (EULAR)-approved criteria, new ACR/EULAR classification criteria for pSS were developed and endorsed in 2016. Salivary gland ultrasonography (SGUS) is a new imaging tool used to detect salivary gland abnormalities in pSS patients. Several reports on the utility of SGUS for pSS diagnosis have appeared. This review focuses on the new 2016 ACR/EULAR classification criteria for pSS and the clinical application of SGUS in patients with pSS.

Keyword

Sjögren's syndrome; Classification; Diagnosis; Salivary glands; Ultrasonography

MeSH Terms

Classification*
Consensus
Diagnosis
Humans
Rheumatic Diseases
Rheumatology
Salivary Glands*
Specialization
Ultrasonography*