Yeungnam Univ J Med.  2017 Jun;34(1):84-87. 10.12701/yujm.2017.34.1.84.

Multifocal nodular lymphoid hyperplasia of the lung

Affiliations
  • 1Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. drhwpark@naver.com
  • 2Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.

Abstract

Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.

Keyword

Lung; Pseudolymphoma; Lymphoproliferative disorder

MeSH Terms

Biopsy
Follow-Up Studies
Hyperplasia*
Lung*
Lymphoproliferative Disorders
Multiple Pulmonary Nodules
Natural History
Pseudolymphoma
Radiography
Thorax
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