Korean J Gastrointest Endosc.  2003 Apr;26(4):226-231.

Two Cases of Small Intestinal Nodular Lymphoid Hyperplasia

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. Syhan@daunet.donga.ac.kr

Abstract

Pseudolymphoma or lymphoid hyperplasia is a rare clinicopathologic disease which occurs in a variety of sites including the skin, orbit, salivary glands, gastrointestinal tract, lung, and other organs. Lymphoid hyperplasia of the gastrointestinal tract can be categorized into four clinicopathologic groups: focal lymphoid hyperplasia of the stomach, focal lymphoid hyperplasia of the small intestine, focal lymphoid hyperplasia of the rectum, and nodular lymphoid hyperplasia of the gastrointestinal tract. We experienced two cases of nodular lymphoid hyperplasia of the small intestine with hypogammaglobulinemia (IgA deficiency) and without hypogammaglobulinemia presented with epigastric discomfort. Esophagogastroduodenoscopy and small bowel series showed 0.2~.5 cm sized small, numerous Yamada-I or Yamada-II polypoid lesions from the duodenal bulb to the terminal ileum in two cases. Histologic finding of the duodenal bulb showed small round mature lymphocyte infiltration and reactive follicle with germinal center in two cases. We report two cases with a brief reviews of literature.

Keyword

Lymphoid hyperplasia; Small intestine

MeSH Terms

Agammaglobulinemia
Endoscopy, Digestive System
Gastrointestinal Tract
Germinal Center
Hyperplasia*
Ileum
Intestine, Small
Lung
Lymphocytes
Orbit
Pseudolymphoma
Rectum
Salivary Glands
Skin
Stomach
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