Asia Pac Allergy.  2012 Oct;2(4):280-282. 10.5415/apallergy.2012.2.4.280.

Biphasic anaphylaxis to gemifloxacin

• Yilmaz I
• DoÄŸan S
• Tutar N
• Kanbay A
• BüyükoÄŸlan H
• Demir R

• KMID: 2397446
• DOI: http://doi.org/10.5415/apallergy.2012.2.4.280

Abstract

Anaphylaxis have been documented as adverse effects of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, and moxifloxacin. However resistant and biphasic anaphlylactic reactions to gemifloxacin have not been reported to date. Management of severe anaphylaxis in the elderly can be complicated by concurrent medications such as beta (β) adrenergic, alpha (α) adrenergic blockers and angiotensin-converting enzyme (ACE) inhibitors. We report here in the case of a 60-year-old male who was taking on ACE inhibitor, α and β blockers and experienced a severe, resistant and biphasic anaphlylactic reaction to gemifloxacin mesylate.

Keyword

Alpha blocker; Beta blocker; Biphasic anaphylaxis; Gemifloxacin; ACE inhibitor

MeSH Terms

Adrenergic Antagonists
Aged
Anaphylaxis*
Ciprofloxacin
Humans
Levofloxacin
Male
Mesylates
Middle Aged
Norfloxacin
Ofloxacin
Adrenergic Antagonists
Ciprofloxacin
Mesylates
Norfloxacin
Ofloxacin

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