Korean J Biol Psychiatry.  2017 Aug;24(3):129-133. 10.0000/kjbp.2017.24.3.129.

Association between Quality of Life and Symptom Severity in Obsessive-Compulsive Disorder Patients Using EQ-5D

• Kim SN
• Moon W
• Han J
• Lee J

• KMID: 2396546
• DOI: http://doi.org/10.0000/kjbp.2017.24.3.129

Abstract

OBJECTIVES
Obsessive-compulsive disorder (OCD) is a disabling psychiatric disorder, and more attention is recently paid on the quality of life (QoL) in OCD patients. The Euro-QoL-5D (EQ-5D) is a widely used self-report to calculate a single score which represents "˜health utilities'. The aim of this study was to assess the health-related QoL for patients with OCD using the EQ-5D and to examine the relationship between health-related QoL and symptom severity.
METHODS
Seventy-three patients with a Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnosis of OCD were recruited from the outpatient clinic in Seoul National University Hospital. Symptom severity was assessed using the Yale-Brown Obsessive-Compulsive Scale (YBOCS), and QoL was assessed with the EQ-5D-5L questionnaire. Using Korean valuation study, a single score of QoL was calculated.
RESULTS
Most of the OCD patients were relatively young (< 45 years) with the mean YBOCS total score of 19.33. The mean EQ-5D score was 0.71 and significantly correlated with symptom severity (r = -0.483, p < 0.001). 25% of the EQ-5D score was predicted by the YBOCS total score (b = -0.011, p < 0.001) by regression analysis.
CONCLUSIONS
OCD patients suffer from lower health-related QoL and QoL significantly decreased as symptom severity increased. The results of the EQ-5D would enable further studies on QoL comparison across medical disease and mental disorders.

Keyword

Quality of life; EQ-5D; Obsessive-compulsive disorder; Symptom severity

MeSH Terms

Ambulatory Care Facilities
Diagnosis
Diagnostic and Statistical Manual of Mental Disorders
Humans
Mental Disorders
Obsessive-Compulsive Disorder*
Quality of Life*
Seoul