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Implementation and Validation of an Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantifying Levetiracetam and Lamotrigine in Serum Specimens

Yi A, Lee JH, Nam HG, Han J, Cho SE, Lee SG, Lee EH

We validated an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for quantifying levetiracetam (LEV) and lamotrigine (LAM) in serum specimens. We developed an UHPLCMS/MS method using Triple Quad 4500MD...
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The Association Between Weekend Catch-Up Sleep and Depression by Age Group in Korean Adults

Kim NR, Han J, Kim TH

Objectives:We aimed to explore weekend catch-up sleep (CUS) by age and to find out the association between CUS and depression by the age group and weekday sleep duration (SD). Methods:Using data...
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Predicting the Response of Neoadjuvant Chemotherapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer With Axillary Lymph Node Metastasis by Multigene Assay

Lee JH, Ryu JM, Ahn JH, Cho SY, Lee SK, Yu J, Chae BJ, Nam SJ, Han J, Lee JE, Kim SW

Purpose: The GenesWell™ breast cancer test (BCT) is a recently developed multigene assay that predicts the risk of distant recurrence in patients with hormone receptor-positive (HR+) and human epidermal growth...
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In Vivo Feasibility Test of a New Flexible Ureteroscopic Robotic System, easyUretero, for Renal Stone Retrieval in a Porcine Model

Kim J, Jung HD, Moon YJ, Han H, Cheon B, Han J, Cho SY, Lee JY, Kwon DS

Purpose: Using a new robotic endoscopic platform system developed for retrograde intrarenal surgery (RIRS) called easyUretero (ROEN Surgical Inc.), we evaluated the feasibility and safety of renal stone retrieval in...
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Listeria monocytogenes endophthalmitis in immunocompromised patient

Han YS, Han J, Kim JD, Choi DL

Background: Listeria monocytogenes is known for pathogen of enteritis. In severe case, Listeria infection can cause meningoencephalitis, corneal ulcer, pneumonia, endocarditis and intrauterine or cervical infections may result spontaneous abortion...
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The usefulness and ergonomics of a new robotic system for flexible ureteroscopy and laser lithotripsy for treating renal stones

Park J, Gwak CH, Kim D, Shin JH, Lim B, Kim J, Cheon B, Han J, Kwon DS, Park HK

Purpose: To investigate the usefulness and ergonomics of a newly developed robotic system for flexible ureteroscopy (easyUretero). Materials and Methods: During in vitro testing, six participants performed renal stone removal four...
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Changing Patterns of Causative Pathogens over Time and Efficacy of Empirical Antibiotic Therapies in Acute Cholangitis with Bacteremia

Jeong HT, Song JE, Kim HG, Han J

Background/Aims: To select appropriate empirical antibiotics, updates on the changes in pathogens are essential. We aimed to investigate the changes in pathogens and their antibiotic susceptibility in acute cholangitis (AC)...
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Mitochondrial energy metabolic transcriptome profiles during cardiac differentiation from mouse and human pluripotent stem cells

Cho SW, Kim HK, Sung JH, Kim Y, Kim JH, Han J

Simultaneous myofibril and mitochondrial development is crucial for the cardiac differentiation of pluripotent stem cells (PSCs). Specifically, mitochondrial energy metabolism (MEM) development in cardiomyocytes is essential for the beating function....
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Modulation of Osteogenic Differentiation of Adipose-Derived Stromal Cells by Co-Treatment with 3, 4’-Dihydroxyflavone, U0126, and N-Acetyl Cysteine

Song K, Yang GM, Han J, Gil M, Dayem AA, Kim K, Lim KM, Kang GH, Kim S, Jang SB, Vellingiri B, Cho SG

Background and Objectives: Flavonoids form the largest group of plant phenols and have various biological and pharma-cological activities. In this study, we investigated the effect of a flavonoid, 3, 4’-dihydroxyflavone...
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Erratum: Role of Intensive Inpatient Rehabilitation for Prevention of Disability after Stroke: The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) Study

Chang WH, Sohn MK, Lee J, Kim DY, Lee SG, Shin YI, Oh GJ, Lee YS, Joo MC, Han EY, Han J, Kim YH

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The Clinical Impact of Advanced Age on the Postoperative Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Analysis Across US Hospitals Between 2011–2017

Lee DU, Fan GH, Chang K, Lee KJ, Han J, Jung D, Kwon J, Karagozian R

Purpose: This study systematically evaluated the implications of advanced age on postsurgical outcomes following gastrectomy for gastric cancer using a national database. Materials and Methods: The 2011–2017 National Inpatient Sample was...
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Burnout and Resilience among Emergency Physicians at Korean University Hospitals during the COVID-19 Pandemic: A Cross-Sectional Analysis

Kim C, Park KH, Eo EK, Kim YM, Eo SK, Han J

Purpose: This study aimed to investigate burnout and resilience among emergency physicians (EPs) at university teaching hospitals during the coronavirus disease (COVID-19) pandemic. Materials and Methods: In April to May 2021,...
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Tumor Microenvironment Modulating Functional Nanoparticles for Effective Cancer Treatments

Shin S, Lee J, Han J, Li F, Ling D, Park W

Cancer is one of the major diseases that threaten human life worldwide. Despite advances in cancer treatment techniques, such as radiation therapy, chemotherapy, targeted therapy, and immunotherapy, it is still...
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Prevalence and treatment of gastric ulcers in Thoroughbred racehorses of Korea

Hwang H, Dong HJ, Han J, Cho S, Kim Y, Lee I

Background: Gastric ulcer is one of the prevalent diseases in racehorses. However, it has not been recognized as important in Korea, and drugs used to treat gastric ulcers are included...
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Intravenous cidofovir as an adjuvant therapy for recurrent upper airway papillomatosis with lung involvement in a child

Won Jy, Kim S, Son YI, Cho JH, Jeon TY, Han J, Kim YJ, Lee JW, Kim J, Ahn K

Recurrent respiratory papillomatosis (RRP) is a chronic disease related to human papillomavirus infection. The standard treatment of RRP is surgical resection of the lesion, but due to frequent recurrence, a...
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Gallic acid-mitochondria targeting sequence-H3R9 induces mitochondria-targeted cytoprotection

Bae Y, Kim GY, Jessa F, Ko KS, Han J

The development of selective targeting of drug molecules towards the mitochondria is an important issue related to therapy efficacy. In this study, we report that gallic acid (GA)-mitochondria targeting sequence...
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CT Findings of Granulomatous Pneumocystis jiroveci Pneumonia in a Patient with Multiple Myeloma

Shin SR, Kim TS, Han J

Although the typical CT findings of Pneumocystis jiroveci pneumonia (PJP) include diffuse or multifocal areas of ground-glass opacities in both lungs, it can also rarely manifest as multiple pulmonary nodules....
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Korea hypertension fact sheet 2021: analysis of nationwide population-based data with special focus on hypertension in women

Kim HC, Lee H, Lee HH, Seo E, Kim E, Han J, Kwon JY, ftKSoH(ERWG

Background: The Korean Society of Hypertension has published the Korea Hypertension Fact Sheet 2021 to provide an overview of the magnitude and management status of hypertension and their recent trends. Methods:...
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Neonatal Type 2 Gaucher Disease with Congenital Ichthyosis: A Case Report

Lee H, Oh J, Han J, Lee MJ, Park J, Baek SH, Yu R, Eun HS, Park MS, Shin JE

Gaucher disease (GD) is a rare autosomal recessive genetic disease. The symptoms and age of onset vary depending on the subtype. Type 2 GD is potentially lethal, and the mean...
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Sentinel Lymph Node Biopsy in Breast Cancer Patients With Pathological Complete Response in the Axillary Lymph Node After Neoadjuvant Chemotherapy

Kim H, Han J, Kim SY, Lee ES, Kang HS, Lee S, Jung SY, Lee E

Purpose: Sentinel lymph node biopsy (SLNB) alone following neoadjuvant chemotherapy (NAC) remains controversial in patients with breast cancer who are initially lymph nodepositive. The present study aimed to evaluate the...
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