Clin Psychopharmacol Neurosci.  2017 Nov;15(4):352-360. 10.9758/cpn.2017.15.4.352.

Psychometric Properties of the Hypomania Checklist-32 in Korean Patients with Mood Disorders

  • 1Department of Psychiatry, Naju National Hospital, Naju, Korea.
  • 2Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
  • 3Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 4Hangang Mental Clinic, Gimpo, Korea.
  • 5Department of Psychiatry, Jeju National University Hospital, Jeju, Korea.
  • 6Department of Psychiatry, Chung-Ang University College of Medicine, Seoul, Korea.
  • 7Department of Psychiatry, National Center for Mental Health, Seoul, Korea.
  • 8Department of Psychiatry, Kyungpook National University School of Medicine, Daegu, Korea.
  • 9Department of Psychiatry, Iksan Hospital, Iksan, Korea.
  • 10Choimyongsu Psychiatric Clinic, Jeonju, Korea.
  • 11Department of Psychiatry, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.


OBJECTIVE: The aim of this study was to examine the validity of the Korean version of the Hypomania Checklist-32, second revision (HCL-32-R2) in mood disorder patients.
A total of 454 patients who diagnosed as mood disorder according to Structured Clinical Interview for DSM-IV Axis I Disorders, clinician version (SCID-CV) (bipolar disorder [BD] I, n=190; BD-II, n=72; and major depressive disorder [MDD], n=192) completed the Korean module of the HCL-32-R2 (KHCL-32-R2).
The KHCL-32-R2 showed a three-factorial structure (eigenvalue >2) that accounted for 43.26% of the total variance. Factor 1 was labeled “active/elated” and included 16 items; factor 2, “irritable/distractible” and included 9 items; and factor 3 was labeled “risk-taking/indulging” and included 9 items. A score of 16 or more on the KHCL-32-R2 total scale score distinguished between BD and MDD, which yielded a sensitivity of 70% and a specificity of 70%. MDD and BD-II also could be differentiated at a cut-off of 15 with maximized sensitivity (0.67) and specificity (0.66). Cronbach’s alpha of KHCL-32-R2 and its subsets (factors 1, 2, and 3) were 0.91, 0.89, 0.81 and 0.79, respectively. Correlations between KHCL-32-R2 and Montgomery-Asberg Depression Rating Scale, Young Mania Rating Scale and Korean version of Mood Disorder Questionnaire were −0.66 (p=0.41), −0.14 (p=0.9), and 0.61 (p < 0.001), respectively.
The KHCL-32-R2 may be a useful tool in distinguishing between bipolar and depressive patients in clinical settings.


HCL-32-R2; Validation; Sensitivity; Specificity; Bipolar disorder; Major depression
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