J Korean Acad Oral Health.  2017 Sep;41(3):188-193. 10.11149/jkaoh.2017.41.3.188.

In vitro antimicrobial activity of different mouthwashes available in Korea

Affiliations
  • 1Department of Oral Microbiology, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.
  • 2Department of Preventive and Public Health Dentistry, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea. mads@gwnu.ac.kr
  • 3Research Institute of Oral Science, Gangneung-Wonju National University, Gangneung, Korea.

Abstract

OBJECTIVES: The purpose
of this study was to compare the oral antimicrobial effects of seven different mouthwashes available in Korea.
METHODS
To examine the antimicrobial effects of the seven mouthwashes, their minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined using broth microdilution methods. Streptococcus mutans ATCC 25175, Lactobacillus acidophilus ATCC 4355, Candida albicans KCTC 7270, and Porphyromonas gingivalis ATCC 33277 were used in this experiment. S. mutans and P. gingivalis were examined using a scanning electron microscope (SEM), after treatment with the mouthwashes containing cetylpyridinium chloride (CPC).
RESULTS
Mouthwashes containing CPC had lower MIC and MBC values against the four microorganisms. Their bactericidal effects were concentration-dependent. S. mutans and C. albicans were highly sensitive to the concentration of CPC in the mouthwashes. According to the SEM observation, the treatment of bacteria with mouthwashes containing CPC, changed the cell surface texture of S. mutans and P. gingivalis.
CONCLUSIONS
Mouthwashes containing CPC showed relatively lower MIC and MBC values under the same conditions against the four microorganisms used in this study.

Keyword

Antimicrobial activity; Mouthwash; Oral microorganisms
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