Korean Circ J.  2016 Sep;46(5):714-718. 10.4070/kcj.2016.46.5.714.

Cardiopulmonary Bypass Priming Using Autologous Cord Blood in Neonatal Congenital Cardiac Surgery

• Choi ES
• Cho S
• Jang WS
• Kim WH

• KMID: 2389630
• DOI: http://doi.org/10.4070/kcj.2016.46.5.714

Abstract

BACKGROUND AND OBJECTIVES
A blood transfusion is almost inevitable in neonatal cardiac surgery. This study aimed to assess the feasibility of using autologous cord blood for a cardiopulmonary bypass (CPB) priming as an alternative to an allo-transfusion in neonatal cardiac surgery.
SUBJECTS AND METHODS
From January 2012 to December 2014, cord blood had been collected during delivery after informed consent and was stored immediately into a blood bank. Eight neonatal patients had their own cord blood used for CPB priming during cardiac surgery.
RESULTS
All patients underwent surgery for their complex congenital heart disease. The median age and body weight at surgery was 11 days (from 0 to 21 days) and 3.2 kg (from 2.2 to 3.7 kg). The median amount and hematocrit of collected cord blood was 72.5 mL (from 43 to 105 mL) and 48.7% (from 32.0 to 51.2%). The median preoperative hematocrit of neonates was 36.5% (from 31.0 to 45.0%); the median volume of CPB priming was 130 mL (From 120 to 140 mL). Seven out of eight patients did not need an allo-transfusion in CPB priming and only one neonate used 20 mL of packed red blood cells in CPB priming to obtain the target hematocrit.
CONCLUSION
Autologous cord blood can be used for CPB priming as alternative to packed red blood cells in neonatal congenital cardiac surgery in order to reduce allo-transfusion.

Keyword

Fetal blood; Cardiopulmonary bypass; Cardiac surgery

MeSH Terms

Blood Banks
Blood Transfusion
Body Weight
Cardiopulmonary Bypass*
Erythrocytes
Fetal Blood*
Heart Defects, Congenital
Hematocrit
Humans
Infant, Newborn
Informed Consent
Thoracic Surgery*

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