Clin Exp Vaccine Res.  2017 Jan;6(1):31-37. 10.7774/cevr.2017.6.1.31.

Psychogenic illness following vaccination: exploratory study of mass vaccination against pandemic influenza A (H1N1) in 2009 in South Korea

• Yang TU
• Kim HJ
• Lee YK
• Park YJ

• KMID: 2366889
• DOI: http://doi.org/10.7774/cevr.2017.6.1.31

Abstract

PURPOSE
Adverse events during mass vaccination campaigns have had a profoundly negative impact on vaccine coverage rates. The objective of the study was to identify the characteristics of reported psychogenic illness cases following mass vaccination that needed further interventions of the national immunization program.
MATERIALS AND METHODS
We collected documents that were submitted to the Korea Centers for Disease Control and Prevention for vaccine injury compensation, and analyzed cases of psychogenic illness following pandemic influenza A (H1N1) vaccination in 2009 which were confirmed by the Korean Advisory Committee on Vaccine Injury Compensation.
RESULTS
During the 2009-2010 influenza season, 13 million Koreans were vaccinated against pandemic influenza. Of 28 reported psychogenic illness cases following immunization, 25 were vaccinated through school-located mass immunization. Significant numbers of them were female adolescents (68%) or had underlying vulnerable conditions or emotional life stressors (36%). They required lengthy hospitalization (median, 7 days) and high medical costs (median, US $1,582 per case).
CONCLUSION
Health authorities and organizers of future mass vaccinations should be well aware of the possible occurrence of psychogenic illness, acknowledge their detailed characteristics, and take its economic burden into account to mitigate the risk of transmission of infectious diseases efficiently.

Keyword

Vaccination; Psychophysiologic disorders; Hysteria; Students; Mass vaccination; Influenza vaccines

MeSH Terms

Adolescent
Advisory Committees
Centers for Disease Control and Prevention (U.S.)
Communicable Diseases
Compensation and Redress
Hospitalization
Humans
Hysteria
Immunization
Immunization Programs
Influenza Vaccines
Influenza, Human*
Korea*
Mass Vaccination*
Pandemics*
Psychophysiologic Disorders
Seasons
Vaccination*
Influenza Vaccines

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