Korean J Pediatr.  2016 Nov;59(Suppl 1):S68-S71. 10.3345/kjp.2016.59.11.S68.

Acute gastritis associated with Epstein-Barr virus infection in a child

  • 1Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea.
  • 2Department of Pathology, Chungnam National University School of Medicine, Daejeon, Korea.
  • 3Department of Pediatircs, Changwon Gyeosang National University Hospital, Changwon, Korea. pedkim@gnuh.co.kr


Infectious mononucleosis is Epstein-Barr virus (EBV) inducing a self-limiting clinical syndrome characterized by fever, sore throat, hepatosplenomegaly, and generalized lymphadenopathy. Gastrointestinal symptoms of EBV infection are nonspecific and occur rarely. EBV inducing acute gastrointestinal pathology is poorly recognized without suspicion. Careful consideration is needed to diagnose gastric involvement of EBV infection including gastric lymphoma, gastric cancer, and gastritis. A few recent cases of gastritis associated with EBV infection have been reported in adolescents and adults. However, there is no report of EBV-associated gastritis in early childhood. We experienced a rare case of 4-year-old girl with EBV gastritis confirmed by in situ hybridization.


Epstein-Barr virus; Gastritis; In situ hybridization; Infectious mononucleosis
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