Gastrointest Interv.  2016 Oct;5(3):159-169. 10.18528/gii.2016.5.3.159.

How to manage gastric polyps

Affiliations
  • 1Department of Gastroenterology, Hepatology, and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Jefflee@mdanderson.org
  • 2Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Abstract

Gastric cancer is the second leading cause of cancer related death in the world. In United States, gastric polyps are found in approximately 6% of upper endoscopy. The incidence of gastric polyps increased with widespread use of esophagogastroduodenoscopy and more liberal use of proton pump inhibitors. They are usually asymptomatic, but infrequently cause symptoms of bleeding, pain and gastric outlet obstruction. It is important to distinguish premalignant conditions and mimickers of malignancy. Helicobacter pylori eradication therapy leads to regression of hyperplastic polyps but it is not clear for adenoma. Endoscopy plays key role not only in diagnosis but also in surveillance. With narrow band imaging and chromo endoscopy, we are much better today in detecting and discerning these. Also, with endoscopic mucosal resection and endoscopic submucosal dissection, we can manage these better. In this review article we will discuss the various diagnostic tools and therapeutic options for hyperplastic polyp, fundic gland polyp, gastrointestinal stromal tumor, adenoma, neuroendocrine tumor, linitis plastica, and intestinal metaplasia.

Keyword

Carcinoid tumor; Endosonography; Helicobacter pylori; Narrow band imaging; Proton pump inhibitors

MeSH Terms

Adenoma
Carcinoid Tumor
Diagnosis
Endoscopy
Endoscopy, Digestive System
Endosonography
Gastric Outlet Obstruction
Gastrointestinal Stromal Tumors
Helicobacter pylori
Hemorrhage
Incidence
Linitis Plastica
Metaplasia
Narrow Band Imaging
Neuroendocrine Tumors
Polyps*
Proton Pump Inhibitors
Stomach Neoplasms
United States
Proton Pump Inhibitors
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