Brain Tumor Res Treat.  2016 Oct;4(2):142-144. 10.14791/btrt.2016.4.2.142.

Multiple Meningocerebral Metastasis and Extensive Skull Metastasis from Squamous Cell Carcinoma of Esophagus: A Case Report and Review of Literature

• Na MK
• Kim CH
• Kim JM
• Cheong JW
• Ryu JI
• Kim HW

• KMID: 2356985
• DOI: http://doi.org/10.14791/btrt.2016.4.2.142

Abstract

Esophageal carcinoma rarely metastasizes to the brain. Although some studies have mentioned esophageal cancer with solitary brain metastasis or with meningocerebral metastasis or with skull metastasis, multiple meningocerebral metastasis and extensive skull metastasis from squamous cell carcinoma of esophagus has not been reported in the literature. We encountered a case of an extensive osteolytic change of the skull and multiple meningocerebral metastases from esophageal carcinoma.

Keyword

Brain metastasis; Esophageal carcinoma

MeSH Terms

Brain
Carcinoma, Squamous Cell*
Epithelial Cells*
Esophageal Neoplasms
Esophagus*
Neoplasm Metastasis*
Skull*

Figure

• 

  Fig. 1 Brain computed tomography scans and skull X-ray showed osteolytic metastasis at vertex and both parietal high-convexities.

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  Fig. 2 Magnetic resonance images with gadolinium enhancement of the patient. A: Axial image shows well-enhanced mass the in right temporal lobe and left parietal lobe. Diffuse dural thickening and enhancement was also noted in bilateral pachymeninges (arrows). Coronal (B) and sagittal (C) images represent the extensive osteolytic lesion in the vault of the skull and enhanced tumor in the left temporal lobe.

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  Fig. 3 CT and Positron emission tomography (PET) scans show esophageal cancer and multiple metastatic lesions. A: Contrast enhanced computed tomography scan of the chest showing diffuse wall thickening of the lower portion of esophagus (arrow). B: PET scans showing multiple metastatic foci in bones, right lung, anastomotic site of esophagus, right, and mesenteric lymph nodes.

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