Clin Psychopharmacol Neurosci.  2016 Nov;14(4):396-398. 10.9758/cpn.2016.14.4.396.

Recurrence of Panic Attacks after Influenza Vaccination: Two Case Reports

  • 1Department of Psychiatry, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.


Human influenza is a contagious respiratory illness caused by the influenza virus. The influenza vaccination is recommended annually, but several adverse effects related to allergic reactions have been reported. Panic attacks are also known to occur, but no case of a panic attack adverse effect has been reported in South Korea. We present two cases of panic disorder patients whose symptoms were aggravated by the influenza vaccination. We assumed that dysregulation of T-lymphocytes in panic disorder patients could have a role in activating various kinds of cytokines and chemokines, which then can lead to panic attack aggravation.


Human influenza; Influenza vaccines; Panic attack; Adverse effects
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