Korean J Anesthesiol.  1984 Dec;17(4):370-376.

Malignant Hyperthermia Syndrome

Affiliations
  • 1Department of Anesthesiology, Hangang Sacred Heart Hospital, Hallym College, Seoul, Korea.

Abstract

MHS is a myopathic disorder transmitted by a dominant autosomal gene. The seriousness of the problem is underscored by the fact that the mortality rate, until recently, has ranked the highest among the complications of modern anesthesia. During halothane anesthesia we experienced a case of MHS with high temperature and rigidity after succinylcholine, observed change of serum electrolytes, and noted CPK and myoglobin in the urine. The patient was managed with surface cooling, bicarbonate, diurectics, mechanical ventilator and corticosteroids. The patient survived without any sequelae and was discharged after 10 days.


MeSH Terms

Adrenal Cortex Hormones
Anesthesia
Electrolytes
Halothane
Humans
Malignant Hyperthermia*
Mortality
Myoglobin
Succinylcholine
Ventilators, Mechanical
Adrenal Cortex Hormones
Electrolytes
Halothane
Myoglobin
Succinylcholine
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