J Korean Neurol Assoc.
2008 Nov;26(4):379-382.
Guillain-Barre Syndrome With anti-GM1 and GD1b Antibodies Following Acute Hepatitis A
- Affiliations
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- 1Department of Neurology, Seoul National University College of Medicine, Seoul, Korea. nrpsh@snu.ac.kr
Abstract
- Guillain-Barre syndrome (GBS) rarely develops following acute viral hepatitis, and there has been no report on the association with anti-ganglioside antibodies. Herein, we report a 36-year-old man who presented with rapidly progressive areflexic quadriparesis following acute viral hepatitis A. The results of nerve conduction study were consistent with demyelinating motor polyneuropathy, and IgG anti-GM1 and anti-GD1b antibodies were positive. Immune responses towards gangliosides may also be important mediators in acute hepatitis A-associated GBS.
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