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Co-occurrence of both maternally inherited neurofibromatosis type 1 and Lesch-Nyhan disease in a child with severe neurodevelopmental impairment

Yun JH, Hong YH, Seo GH, Shin YL

Lesch-Nyhan disease (LND) is a rare X-linked recessive inherited purine metabolic disorder that accompanies neurodevelopmental problems. Neurofibromatosis type 1 (NF1) is a relatively common autosomal dominant inherited genetic disorder characterized...
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Microbiology of Human Follicular Fluid and the Vagina and Its Impact on in Vitro Fertilization Outcomes

Kim SM, Won KH, Hong YH, Kim SK, Lee JR, Jee BC, Suh CS

Purpose: The present study aimed to identify microorganisms in follicular fluids and to investigate their association with in vitro fertilization (IVF) outcomes. Materials and Methods: This study was conducted as a...
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Comparison of Initial Presentation of Pediatric Diabetes Before and During the Coronavirus Disease 2019 Pandemic Era

Lee Y, Kim M, Oh K, Kang E, Rhie YJ, Lee J, Hong YH, Shin YL, Kim JH

Background: Hospital visitation has become challenging during the coronavirus disease 2019 pandemic because of quarantine measures and fear of infection. Consequently, newly diagnosed patients may present with more severe diseases...
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Efficacy and Safety of Pregabalin for Muscle Cramps in Liver Cirrhosis: A Double-Blind Randomized Controlled Trial

Ahn S, Hong YH, Lee DH, Joo SK, Jung YJ, Sohn SY, Choi K, Kim W

Background: Muscle cramp is possibly related to peripheral nerve hyperexcitability (PNH), and one of the most debilitating symptoms frequently encountered in patients with liver cirrhosis. We investigated whether pregabalin, a...
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Survival, Prognosis, and Clinical Feature of Refractory Myasthenia Gravis: a 15-year Nationwide Cohort Study

Jeong S, Noh Y, Oh IS, Hong YH, Shin JY

Background: Myasthenia gravis (MG) is a rare classic autoimmune disease where immunosuppressant therapies have been successful to reduce MG attributable mortality fairly well. However, patients with refractory MG (rMG) among...
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Acute-Onset Sensory Ataxic Polyradiculopathy With Root Enhancement in Spine MRI

Kwon KH, Hong Yh, Song MJ, Cho SJ

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2020 Korean Society for the Study of Obesity Guidelines for the Management of Obesity in Korea

Kim BY, Kang SM, Kang JH, Kang SY, Kim KK, Kim KB, Kim B, Kim SJ, Kim YH, Kim JH, Kim JH, Kim EM, Nam GE, Park JY, Son JW, Shin YA, Shin HJ, Oh TJ, Lee H, Jeon EJ, Chung S, Hong YH, Kim CH, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)

Obesity is a prevalent and complex disease. The prevalence of obesity in Korea increased from 29.7% in 2010 to 35.7% in 2018, with the prevalence of abdominal obesity being 23.8%...
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Large for Gestational Age and Obesity-Related Comorbidities

Hong YH, Lee JE

Both small for gestational age and large for gestational age (LGA) size at birth are associated with metabolic complications throughout life. The long-term consequences of LGA have been investigated in...
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Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling

Shin HY, Han KS, Park HW, Hong YH, Kim Y, Moon HE, Park KW, Park HR, Lee CJ, Lee K, Kim SJ, Heo MS, Park SH, Kim DG, Paek SH

  • KMID: 2515812
  • Exp Neurobiol.
  • 2021 Apr;30(2):120-143.
  • doi: 10.5607/en21004
Central neurocytoma (CN) has been known as a benign neuronal tumor. In rare cases, CN undergoes malignant transformation to glioblastomas (GBM). Here we examined its cellular origin by characterizing differentiation...
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A Patient With Late-onset Limb-girdle Muscular Dystrophy Type 2B Mimicking Dermatomyositis: A Case Report and Review

Kim MJ, Oh YJ, Hong YH, Park SH, Oh JS, Kim MJ, Chae JH, Shin K

Limb-Girdle Muscular Dystrophy 2B (LGMD2B) presents with proximal and/or distal muscle weakness and markedly high creatine kinase level. It is caused by the loss of dysferlin due to mutations in...
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Impact of imatinib or dasatinib coadministration on in vitro preantral follicle development and oocyte acquisition in cyclophosphamide-treated mice

Hong YH, Kim SJ, Kim SK, Lee SC, Jun JH, Jee BC, Kim SH

Objective: We investigated the impact of tyrosine kinase inhibitor (imatinib or dasatinib) coadministration with cyclophosphamide (Cp) on preantral follicle development in an in vitro mouse model. Methods: Seventy-three female BDF1 mice...
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Efficacy of dual progesterone administration (intramuscular and vaginal) for luteal support in fresh day 3 or day 4 embryo transfer cycles

Nho EJ, Hong YH, Park JH, Kim SK, Lee JR, Jee BC, Kim SH

Objective The aim of this study was to compare in vitro fertilization outcomes between fresh day 3 or day 4 embryo transfer cycles with dual progesterone (P) administration (intramuscular and...
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Optimal numbers of mature oocytes to produce at least one or multiple top-quality day-3 embryos in normal responders

Shim YJ, Hong YH, Kim SK, Jee BC

Objective We attempted to identify the optimal cutoff numbers of mature oocytes that would produce at least one or multiple top-quality (grade A) day-3 embryos in normal responders undergoing stimulated...
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Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review

Song KS, Kim MJ, Lim HK, Hong YH, Park SS, Hong CW, Park SC, Sohn DK, Han KS, Oh JH

Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition. We report a case of small bowel...
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Technique of Biportal Endoscopic Transforaminal Lumbar Interbody Fusion

Heo DH, Hong YH, Lee DC, Chung HJ, Park CK

Biportal endoscopic transforaminal lumbar interbody fusion (TLIF) may have advantages of minimally invasive fusion surgery as well as those of endoscopic surgery. The purpose of this study was to present...
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Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids

Mun SJ, Hong YH, Ahn HS, Ryu JS, Chung KS, Son MJ

A human cell-based liver model capable of long-term expansion and mature hepatic function is a fundamental requirement for pre-clinical drug development. We previously established self-renewing and functionally mature human pluripotent...
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Current Long-Term Pharmacotherapies for the Management of Obesity

Kim BY, Kang SM, Kang JH, Kim KK, Kim B, Kim SJ, Kim YH, Kim JH, Kim JH, Nam GE, Park JY, Son JW, Shin HJ, Oh TJ, Lee H, Jeon EJ, Chung S, Hong YH, Kim CH, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)

Obesity is a serious and growing worldwide health challenge associated with type 2 diabetes mellitus, cardiovascular disease, osteoarthritis, some cancers, sleep apnea, asthma, and nonalcoholic fatty liver. The Korean Society...
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A Study on the Knowledge and Performance Status for Healthcare- Associated Infection Control and Prevention in Caregivers

Cho HJ, Hong YH

Background: This study aimed to provide basic data for policy making and the improvement of infection control-related business practices, to standardize caregivers’ duties and qualification requirements by investigating their knowledge...
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Associations of post-warming embryo or blastocyst development with clinical pregnancy in vitrified embryo or blastocyst transfer cycles

Hong YH, Lee JM, Kim SK, Youm HW, Jee BC

Objective: To investigate whether the degree of post-warming embryo or blastocyst development is associated with clinical pregnancy in vitrified embryo or blastocyst transfer cycles. Methods: Ninety-six vitrified cleavage-stage embryos and 58...
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Prevalence and Incidence of Neuromyelitis Optica Spectrum Disorderin Korea: Population Based Study

Lee HL, Kim JY, Seok JM, Hong YH, Lim NG, Shin HY, Kim BJ, Hwang SY, Min JH, Kim BJ

Background: Although neuromyelitis optica spectrum disorder (NMOSD) is known to be a rare disease, its prevalence and incidence have not yet been studied in Korea. We performed a population-based study...
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