J Korean Neurol Assoc.  2008 Nov;26(4):376-378.

Acute Marchiafava-Bignami Disease With Typical White Matter Involvement on Diffusion Weighted MRI

Affiliations
  • 1Department of Neurology, Eulji University School of Medicine, Daejeon, Korea. trumind@lycos.co.kr

Abstract

Marchiafava-Bignami disease (MBD) is characterized by cerebral white matter lesions associated with chronic alcoholism. Premortem diagnosis of MBD is usually based on history and clinical manifestations. We report a case of acute MBD in which diffusion-weighted MRI (DWI) showed high signal intensities along the white matter including the corpus callosum. DWI may be useful in premortem diagnosis of acute MBD.

Keyword

Marchiafava-Bignami disease; White matter disease; DWI

MeSH Terms

Alcoholism
Corpus Callosum
Diffusion
Diffusion Magnetic Resonance Imaging
Humans
Leukoencephalopathies
Marchiafava-Bignami Disease
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