J Korean Neurol Assoc.
2002 May;20(3):279-282.
A Case of Central Nervous System Langerhans Cell Histiocytosis: Brain MRI Findings and Clinical Course
- Affiliations
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- 1Department of Neurology, College of Medicine, Seoul National University, Korea. kminlee@snu.ac.kr
Abstract
- A 28-year-old man with Langerhans cell histiocytosis of the gastric wall and hypophysial infundibulum had received local radiation therapy to the infundibulum. Eight months later he presented with left inferior temporal quadrantanopsia of the left eye. Brain MRI revealed multiple nodular enhancing lesions involving brainstem, left external capsule, both temporal lobes, prechiasmatic optic nerves and basal ganglia. After dexamethasone chemotherapy there had been partial remission. During tapering dexamethasone the symptom aggravated and then despite etoposide chemotherapy the size and number of lesions increased.
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