J Korean Neuropsychiatr Assoc.
2006 Mar;45(2):93-99.
Clinical Characteristics and Treatment Strategies in Female Patients with Obsessive-Compulsive Disorder
- Affiliations
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- 1Department of Neuropsychiatry, Hallym University College of Medicine, Anyang, Korea.
- 2Department of Psychiatry, College of Medicine, Yonsei University, Seoul, Korea. spr88@yumc.yonsei.ac.kr
- 3Institute of Behavioral Science in Medicine, College of Medicine, Yonsei University, Seoul, Korea.
Abstract
- This article reviews clinical characteristics, neurobiological aspects and treatment strategies in female patient with obsessive-compulsive disorder (OCD) compared to male. Female with OCD had a later age of onset and different patterns of OCD symptomatology and comorbidity. Female with OCD showed more favorable course and also reported more frequently stressful event in preceding OCD onset. The onset or worsening of OCD was related to female reproductive cycle events, especially at menarche and postpartum. There is a paucity of investigation regarding gender difference in treatment response in OCD. It has been suggested that gender may contribute to the clinical and biological heterogeneity of OCD and also sexually dimorphic pattern of genetic susceptibility to OCD may be present.
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