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Genetic predisposition of variant angina

Kim HS

  • KMID: 1652682
  • Korean J Med.
  • 2004 Apr;66(4):369-372.
No abstract available.
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Obesity : Genetic vs Environmental Factors

Lee SI, Jung HY

  • KMID: 2025726
  • J Korean Soc Biol Psychiatry.
  • 2003 Jun;10(1):45-53.
Debates relevant to the etiology of weight gain or obesity, i.e., the dichotomous understandings about whether obesity arises from the genetic predisposition or from the environmental influences, has long existed....
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Molecular Genetics of Cerebral Aneurysm

Ahn JY, Kim JK

  • KMID: 1932129
  • Korean J Cerebrovasc Surg.
  • 2003 Mar;5(1):12-16.
Subarachnoid hemorrhage(SAH) secondary to ruptured cerebral aneurysm is a complex trait, with both genetic and environmental risk factors playing an important part. The 30-day mortality rate of patients with SAH...
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New insights into the genetics of fibromyalgia

Park DJ, Lee SS

Although debate on the concept of fibromyalgia (FM) has been vigorous ever since the classification criteria were first published, FM is now better understood and has become recognized as a...
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Genetic Role in Allergic Rhinitis

Lee JH, Koh SH

  • KMID: 2297616
  • J Rhinol.
  • 2010 May;17(1):7-12.
Allergic rhinitis is an inflammatory disease of the nasal mucosa, induced by an IgE-mediated reaction following exposure to an allergen. Allergic rhinitis is a global health problem, with a prevalence...
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Genetic risk factors associated with respiratory distress syndrome

Jo HS

Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect...
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Genetic predisposition for atopy and allergic rhinitis in the Singapore Chinese population

Wang DY

The prevalence of allergic diseases is high globally, but especially in developed countries, with one in five to one in four individuals affected worldwide. The World Health Organization's "Allergic Rhinitis...
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Etiology, Pathogenesis and Natural Course of Chronic Pancreatitis

Hyun JJ, Lee HS

  • KMID: 2263493
  • Korean J Med.
  • 2012 Jul;83(1):1-17.
The etiology of chronic pancreatitis varies greatly as demonstrated in the TIGAR-O classification. However, due to the lack of correlation and reproducibility between the etiologic factors and the presentation of...
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Genetic Susceptibility to Lung Cancer in Koreans

Park JY

  • KMID: 1972961
  • Cancer Res Treat.
  • 2002 Feb;34(1):8-12.
No abstract available.
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The Relationship between Interleukin-1beta Gene Polymorphism and Partial Epilepsy

Lee W, Kim MA, Kim SJ, Kim SE

  • KMID: 2343056
  • J Korean Neurol Assoc.
  • 2003 Oct;21(5):473-478.
BACKGROUND: Neuronal cell death, reactive gliosis, enhanced neurogenesis, and axonal sprouting are well-known pathogenetic mechanisms of epileptogenesis. Pro-inflammatory cytokines are known to modulate the process of epileptogenesis. Interleukin (IL)-1beta-511*2 allele...
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Gut Microbiota in Inflammatory Bowel Disease

Shim JO

The gut mucosal barrier plays an important role in maintaining a delicate immune homeostasis. The pathogenesis of inflammatory bowel disease (IBD) is considered to involve a defective mucosal immunity along...
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Predisposition of genetic disease by modestly decreased expression of GCH1 mutant allele

Kim YS, Choi YB, Lee JH, Yang SH, Cho JH, Shin CH, Lee SD, Paik MK, Hong KM

Recently it was shown that single nucleotide polymorphisms (SNPs) can explain individual variation because of the small changes of the gene expression level and that the 50% decreased expression of...
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Genetic Polymorphism Predisposing to Differentiated Thyroid Cancer: A Review of Major Findings of the Genome-Wide Association Studies

Saenko VA, Rogounovitch TI

Thyroid cancer has one of the highest hereditary component among human malignancies as seen in medical epidemiology investigations, suggesting the potential meaningfulness of genetic studies. Here we review researches into...
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Type 1 diabetes genetic susceptibility markers and their functional implications

Park Y

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by selective destruction of pancreatic beta-cells resulting in insulin deficiency. The genetic determinants of T1D susceptibility have been linked to...
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Osteochondritis Dissecans of the Knee Associated with Gout: A Case Report

Seong I, Yang M, Kim T, Kim S, Lee M, Seong S

  • KMID: 2064693
  • J Korean Knee Soc.
  • 1998 Dec;10(2):249-253.
Osteochondritis dissecans of the knee occurs twice as often in males as in females. The peak incidence is about fifteen years of age, and most patients are first diagnosed before...
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Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans

Park HY, Choi HJ, Hong YC

Contribution of genetic predisposition to risk prediction of type 2 diabetes mellitus (T2DM) was investigated using a prospective study in middle-aged adults in Korea. From a community cohort of 6,257...
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Diffuse panbronchiolitis in an adolescent female

Kim HY, Son SK, Park HJ

Diffuse panbronchiolitis (DPB) is a progressive inflammatory respiratory disease of unknown cause mainly occurring in East Asian people. Studies on causes of the disease point to a genetic predisposition unique...
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Atopic Dermatitis and Epidermal Barrier

Lee HH

  • KMID: 2314937
  • Pediatr Allergy Respir Dis.
  • 2009 Jun;19(2):95-105.
Atopic dermatitis (AD) is a multifactorial, chronic inflammatory skin disease in which genetic mutations and cutaneous hyperreactivity to environment stimuli play a role. The skin barrier is known to be...
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Genetic predisposition in nonalcoholic fatty liver disease

Sookoian S, Pirola CJ

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when...
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Exploring Genetic Susceptibility to Fibromyalgia

Park DJ, Kang JH, Yim YR, Kim JE, Lee JW, Lee KE, Wen L, Kim TJ, Park YW, Lee SS

Fibromyalgia (FM) affects 1% to 5% of the population, and approximately 90% of the affected individuals are women. FM patients experience impaired quality of life and the disorder places a...
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